Senior Director, Medical Affairs

Role Summary

Senior Director of Medical Affairs to support the lead oncology program in its first pivotal study. Responsible for hands-on Medical Affairs execution, vendor management, budgets and timelines, and high-quality deliverables across medical information, field operations, and evidence-generation partners. Leads a global MSL team, drives field engagement, site activation, and enrollment acceleration; coordinates patient advocacy and cross-functional communication to support late-stage development and future commercialization. Location: Boston, MA. Travel: Frequent travel to build relationships with KOLs and attend scientific meetings.

Responsibilities

• Manage MSL vendor(s), defining scope, coverage, and performance expectations
• Provides strategic and operational leadership to a global MSL team, fostering alignment, collaboration, and high-quality scientific exchange across diverse regions and healthcare systems
• Provide scientific training through quarterly sessions and ongoing data updates
• Monitor MSL activities, KOL engagement quality, and field insights; translate findings into strategic recommendations
• Direct MSL priorities for investigator education and enrollment acceleration at underperforming sites
• Map priority KOLs by region with specific engagement objectives for MSL execution
• Manage advisory boards to gather insights and validate strategy
• Develop publication plans with journal targets, authors, and timelines
• Create compliant medical education materials (slide decks, data summaries, FAQs) for MSL field use
• Represent Tango at 4-6 major congresses annually
• Build patient advocacy function through partner identification and engagement planning
• Partner with Clinical Operations on site strategy and investigator support
• Comfortable with frequent travel to build strong relationships with KOLs and actively participate in scientific meetings and major industry conferences

Qualifications

• MD, PhD, or equivalent advanced scientific degree
• Minimum of 10 years of experience in Medical Affairs within biotech/pharma
• Deep expertise in oncology and strong experience in late-stage clinical development and product launch preparation
• Experience in building and leading high-performing Medical Affairs teams, including MSLs and vendor management
• Knowledge of applicable global regulatory and compliance frameworks (FDA, EMA, GCP, ICH)
• Strong network of Oncology KOLs, health authorities, and scientific organizations, and demonstrated success in engaging these stakeholders
• Ability to travel regularly to our Boston headquarters