Senior Director Health Economics and Outcomes Research (HEOR)
Vor Bio
3 hours ago
Remote friendly (Boston, MA)
United States
Market Access
Role Summary
The Senior Director, HEOR leads the strategy and execution of health economics, real‑world evidence (RWE), and value demonstration activities to support global and US market access for the company’s lead asset(s). Reports to the Chief Medical Affairs Officer and contributes to launch readiness.
Key Responsibilities
- Develop and own global and US HEOR strategy aligned with clinical development, Medical Affairs, and Market Access.
- Build a HEOR roadmap: burden of illness, cost‑of‑illness, treatment patterns, PRO strategy, economic models, and RWE plans.
- Serve as internal expert on value, evidence, and payer expectations.
- Design and oversee RWE studies (natural history studies, chart reviews, registries, external data collaborations).
- Lead PRO/COA development and validation for regulatory and payer use.
- Partner with Clinical Development to ensure trial endpoints relevant to payers/HTA/patient communities.
- Manage vendors to ensure rigor, compliance, and timely delivery.
- Lead global value dossiers (GVDs), AMCP dossiers, payer evidence decks, and HTA submissions.
- Build cost-effectiveness, budget impact, and scenario models for pricing/reimbursement.
- Provide HEOR insights to pricing strategy and competitive landscape.
- Support payer and HTA engagements.
- Collaborate cross-functionally (Medical Affairs, Market Access, Patient Advocacy, Regulatory Affairs) and support launch planning.
- Represent the company externally; present findings in congresses/publications.
Qualifications
- Advanced degree (PhD, PharmD, MD, MPH, MS) in health economics, epidemiology, outcomes research, public health, or related field.
- 10+ years HEOR/RWE experience in biotech/pharma; 5+ years in leadership/strategic role.
- Demonstrated success supporting pre‑launch and launch activities (ideally rare disease/specialty therapeutics).
- Deep expertise in economic modeling, RWE methodologies, PRO/COA development, and payer/HTA evidence requirements.
- Ability to operate in lean, ambiguous, high‑growth environments.
- Strong vendor management, scientific writing, and communication skills.
- Experience in rare disease/autoimmune/high‑cost specialty products.
- Familiarity with US and ex‑US pricing/reimbursement.
Benefits
- Comprehensive health coverage, flexible paid time off, generous parental leave, and competitive 401(k); education assistance, wellness resources, and financial security.
Application Instructions
- Please visit https://www.vorbio.com/.
The Senior Director, HEOR leads the strategy and execution of health economics, real‑world evidence (RWE), and value demonstration activities to support global and US market access for the company’s lead asset(s). Reports to the Chief Medical Affairs Officer and contributes to launch readiness.
Key Responsibilities
- Develop and own global and US HEOR strategy aligned with clinical development, Medical Affairs, and Market Access.
- Build a HEOR roadmap: burden of illness, cost‑of‑illness, treatment patterns, PRO strategy, economic models, and RWE plans.
- Serve as internal expert on value, evidence, and payer expectations.
- Design and oversee RWE studies (natural history studies, chart reviews, registries, external data collaborations).
- Lead PRO/COA development and validation for regulatory and payer use.
- Partner with Clinical Development to ensure trial endpoints relevant to payers/HTA/patient communities.
- Manage vendors to ensure rigor, compliance, and timely delivery.
- Lead global value dossiers (GVDs), AMCP dossiers, payer evidence decks, and HTA submissions.
- Build cost-effectiveness, budget impact, and scenario models for pricing/reimbursement.
- Provide HEOR insights to pricing strategy and competitive landscape.
- Support payer and HTA engagements.
- Collaborate cross-functionally (Medical Affairs, Market Access, Patient Advocacy, Regulatory Affairs) and support launch planning.
- Represent the company externally; present findings in congresses/publications.
Qualifications
- Advanced degree (PhD, PharmD, MD, MPH, MS) in health economics, epidemiology, outcomes research, public health, or related field.
- 10+ years HEOR/RWE experience in biotech/pharma; 5+ years in leadership/strategic role.
- Demonstrated success supporting pre‑launch and launch activities (ideally rare disease/specialty therapeutics).
- Deep expertise in economic modeling, RWE methodologies, PRO/COA development, and payer/HTA evidence requirements.
- Ability to operate in lean, ambiguous, high‑growth environments.
- Strong vendor management, scientific writing, and communication skills.
- Experience in rare disease/autoimmune/high‑cost specialty products.
- Familiarity with US and ex‑US pricing/reimbursement.
Benefits
- Comprehensive health coverage, flexible paid time off, generous parental leave, and competitive 401(k); education assistance, wellness resources, and financial security.
Application Instructions
- Please visit https://www.vorbio.com/.