Senior Director, GRA Initiatives Project Management Office

Role Summary

The Senior Director, GRA Initiatives PMO leads a team responsible for managing key regulatory projects that support Takeda’s strategic priorities. This role provides strategic direction for the planning and execution of high-impact initiatives, ensuring they are aligned with both GRA and enterprise-level goals. The Senior Director builds and guides a high-performing PMO team, fosters collaboration across functions, and serves as a trusted advisor to GRA leadership. By translating business needs into clear, actionable plans, this leader helps drive measurable outcomes and lasting impact across the organization. Location: Massachusetts - Virtual.

Responsibilities

• Lead and manage the GRA PMO team, providing strategic direction, coaching, and oversight to ensure excellence in project execution and process improvement.
• Serve as the primary liaison to the GRA Leadership Team, driving priority setting, goal alignment, and strategic planning.
• Oversee the full portfolio of GRA PMO initiatives, ensuring alignment with regulatory strategy, operational goals, and enterprise transformation.
• Establish and continuously improve PMO frameworks, tools, and methodologies to support consistent, scalable, and transparent project delivery.
• Guide the development and execution of business cases for GRA initiatives, ensuring alignment with organizational objectives and delivery of meaningful business value.
• Foster a culture of continuous improvement, operational excellence, and professional growth within the PMO.
• Ensure effective stakeholder engagement and change management across GRA and partner organizations.
• Champion user adoption and communication strategies that clearly articulate the impact of GRA initiatives to internal and external stakeholders.
• Monitor initiative performance, risks, and outcomes; report progress to senior leadership and recommend course corrections as needed.
• Represent the GRA PMO in enterprise.

Qualifications

• Bachelor’s degree in Life Sciences, Business, or related field; advanced degree preferred.
• 12+ years of experience in pharmaceutical/biotech industry, with 8+ years in regulatory affairs or R&D operations.
• Proven track record of leading PMO functions and driving strategic change.
• Strong communication, stakeholder management, and organizational skills.
• Experience in global drug development and regulatory strategy.
• PMP or equivalent certification
• Strategic Leadership Ability to set vision and direction for the PMO aligned with GRA and enterprise goals.
• Organizational Influence Skilled in engaging senior leaders and driving consensus across diverse stakeholder groups.
• Talent Development Commitment to mentoring and growing high-performing teams.
• Storytelling & Communication Proficient in crafting compelling narratives to convey strategic value and impact.
• Project & Portfolio Management Expertise in managing complex portfolios and ensuring delivery excellence.
• Change Leadership Ability to lead organizational change and foster adoption of new initiatives.
• Business Acumen Strong understanding of regulatory affairs and enterprise strategy.
• Analytical Thinking Capable of synthesizing data and insights to inform decision-making.