Senior Director, Clinical Research-Medical Director (Oncology)
Vir Biotechnology, Inc.
August 22, 2026
Remote friendly (San Francisco, CA)
United States
Clinical Research and Development
THE OPPORTUNITY
The Senior Director, Clinical Research (Oncology) will serve as a Medical Director/Medical Monitor within Oncology Clinical Development, providing medical leadership for ongoing clinical trials and ensuring patient safety across Vir Bio’s oncology studies.
What You'll Do
- Serve as lead Medical Monitor and Clinical Research Physician for one or more oncology clinical trials, providing ongoing medical oversight and patient-level clinical decision-making
- Review and interpret emerging safety/efficacy data; assess adverse events and safety signals; partner with Pharmacovigilance on benefit-risk and patient safety
- Act as primary medical contact for investigators and study sites for eligibility, safety management, protocol implementation, and complex clinical questions
- Lead medical monitoring activities across Phase 1–3 studies to ensure high-quality conduct, data integrity, protocol compliance, and regulatory readiness
- Contribute to protocols, amendments, informed consent forms, safety management plans, clinical study reports, and regulatory submission content
- Partner cross-functionally (Clinical Operations, Clinical Scientists, Biometrics, Regulatory, Translational Medicine, Safety)
- Present findings and safety updates to governance/executive/external stakeholders, including regulators as needed
- Participate in investigator meetings, safety committees, advisory boards, and regulatory interactions
- Mentor junior team members
Who You Are And What You Bring
- MD required; board certification in Oncology/Hematology-Oncology or related specialty strongly preferred
- 12+ years clinical research and drug development experience
- Deep experience as Medical Monitor/Clinical Research Physician in oncology drug development
- Strong oncology patient safety oversight; experience across Phase 1–3
- Experience reviewing patient-level safety/efficacy data
- Strong knowledge of oncology trial design, GCP/ICH, regulatory requirements, and safety reporting
- Experience partnering with Pharmacovigilance on safety signal detection and benefit-risk assessments
- Regulatory submission and health authority interaction experience preferred
- Excellent communication skills; ability to engage investigators and cross-functional teams
Benefits / Application
- Expected salary range: $235,500 to $329,500 per year.
- Role located in San Francisco headquarters; at least 3 days/week in office.
- Applicants must be authorized to work in the U.S.; company unable to sponsor employment Visa at this time.
The Senior Director, Clinical Research (Oncology) will serve as a Medical Director/Medical Monitor within Oncology Clinical Development, providing medical leadership for ongoing clinical trials and ensuring patient safety across Vir Bio’s oncology studies.
What You'll Do
- Serve as lead Medical Monitor and Clinical Research Physician for one or more oncology clinical trials, providing ongoing medical oversight and patient-level clinical decision-making
- Review and interpret emerging safety/efficacy data; assess adverse events and safety signals; partner with Pharmacovigilance on benefit-risk and patient safety
- Act as primary medical contact for investigators and study sites for eligibility, safety management, protocol implementation, and complex clinical questions
- Lead medical monitoring activities across Phase 1–3 studies to ensure high-quality conduct, data integrity, protocol compliance, and regulatory readiness
- Contribute to protocols, amendments, informed consent forms, safety management plans, clinical study reports, and regulatory submission content
- Partner cross-functionally (Clinical Operations, Clinical Scientists, Biometrics, Regulatory, Translational Medicine, Safety)
- Present findings and safety updates to governance/executive/external stakeholders, including regulators as needed
- Participate in investigator meetings, safety committees, advisory boards, and regulatory interactions
- Mentor junior team members
Who You Are And What You Bring
- MD required; board certification in Oncology/Hematology-Oncology or related specialty strongly preferred
- 12+ years clinical research and drug development experience
- Deep experience as Medical Monitor/Clinical Research Physician in oncology drug development
- Strong oncology patient safety oversight; experience across Phase 1–3
- Experience reviewing patient-level safety/efficacy data
- Strong knowledge of oncology trial design, GCP/ICH, regulatory requirements, and safety reporting
- Experience partnering with Pharmacovigilance on safety signal detection and benefit-risk assessments
- Regulatory submission and health authority interaction experience preferred
- Excellent communication skills; ability to engage investigators and cross-functional teams
Benefits / Application
- Expected salary range: $235,500 to $329,500 per year.
- Role located in San Francisco headquarters; at least 3 days/week in office.
- Applicants must be authorized to work in the U.S.; company unable to sponsor employment Visa at this time.