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Senior Director, Clinical Practice Liaisons

Madrigal Pharmaceuticals
Remote friendly (St Louis, MO)
United States
$262,000 - $320,000 USD yearly
Medical Affairs

Role Summary

The Sr. Director, Clinical Practice Liaison (CPL) is a key field-based leadership position responsible for the strategic and tactical oversight of the CPL team within a defined U.S. region. This individual will play a critical role in managing and developing CPLs, ensuring the team executes against the companyβ€šΓ„Γ΄s medical strategy, complies with regulatory and internal policies, and delivers scientific value to both internal and external stakeholders. This position will interface regularly and compliantly with cross-functional colleagues and external partners, including Thought Leaders, healthcare decision-makers, and other relevant stakeholders.

Responsibilities

  • Team Leadership & Development
  • Recruit, coach, and manage performance of regional CPLs
  • Foster continuous development through mentoring and training
  • Align CPL activities with strategic objectives and tactical plans
  • Medical Strategy Execution
  • Drive implementation of regional field medical strategies
  • Translate national objectives into actionable, regionally tailored activities
  • Partner with cross-functional teams to integrate field insights into medical planning
  • Cross-functional Collaboration
  • Collaborate closely with Sales, Marketing, Market Access, and Clinical Operations
  • Serve as a field-based liaison for HQ Medical Affairs initiatives
  • Contribute to launch readiness and lifecycle management strategies
  • Clinical Trial Support
  • Collaborate with Clinical Operations to ensure successful study execution based upon recognized needs
  • Congress & External Engagement
  • Represent Medical Affairs at U.S. medical congresses in a compliant manner
  • Coordinate booth planning, scientific exchange, competitive intelligence, and post-conference debriefs
  • Strategic Team Building
  • Contribute to the design and structure of the U.S. Field Medical team
  • Identify evolving business needs and adjust regional capabilities accordingly
  • Compliance & Quality
  • Ensure all CPL activities comply with company SOPs, industry standards, and applicable regulations
  • Uphold the highest ethical standards in all external engagements
  • Travel Requirement
  • Willingness to travel 25β€šΓ„Γ¬75% for congresses, site visits, and stakeholder engagement

Qualifications

  • Advanced degree in a scientific or healthcare discipline (MD, PharmD, PhD, DNP, etc.)
  • Minimum 5 years of Medical Affairs experience, including at least 3 years as an MSL or equivalent (translatable clinical practice experience will be considered)
  • Minimum 3 years of people management experience or formal leadership development participation
  • In-depth knowledge of clinical medicine and medical research; experience in cardiometabolic health, or MASH/NASH preferred
  • Proven ability to understand, communicate, and translate complex scientific information
  • Strong knowledge of U.S. healthcare system, FDA regulations, and medical affairs compliance standards
  • Demonstrated cross-functional collaboration, project execution, and strategic planning skills
  • Proficiency in Microsoft Office Suite, virtual communication platforms (e.g., Zoom), and CRM systems (e.g., Veeva)

Preferred Attributes

  • Strong interpersonal, presentation, and relationship-building skills
  • Adaptable and proactive in a fast-paced, evolving environment
  • Passion for mentoring, team building, and field-based medical innovation
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