Senior Director, Clinical Operations
Janux Therapeutics
August 22, 2026
Remote friendly (San Diego County, CA)
United States
Clinical Research and Development
Essential Functions and Responsibilities:
- Drive global clinical operations strategy and execution for programs supporting IND-enabling through Phase 3 objectives and future clinical development plans.
- Collaborate cross-functionally with senior leadership to ensure operational initiatives align with company goals.
- Establish and refine scalable best practices to improve efficiency.
- Oversee development/review/implementation of study documents (protocols, informed consent forms, CRFs, monitoring plans, pharmacy manuals).
- Manage external partner relationships (CROs, central labs, patient advocacy groups) to ensure on-time, within-budget, quality deliverables.
- Provide program updates; establish KPIs/dashboards; present to study teams; represent Clinical Operations in internal/external meetings.
- Mentor and support direct reports; foster professional development and team culture.
- Oversee site strategy and relationships with investigators and key opinion leaders.
- Contribute to SOPs, work instructions, and operational plans to enhance compliance and efficiency.
- Develop operational plans, timelines, and budgets.
- Ensure all trial activities follow protocol, SOPs, GCP, and applicable regulations.
Required Education, Experience, Skills, and Abilities:
- Bachelor’s in life sciences or related field; 12+ years clinical research with 10+ years clinical trial management; advanced degree preferred.
- Strong experience in complex autoimmune indications; early phase preferred.
- Ability to define strategy and execute global clinical operations plans.
- Track record leading complex clinical programs start to completion.
- Strong knowledge of ICH-GCP and FDA/global regulatory guidelines.
- Proficiency with MS Office and clinical trial systems (CTMS, eTMF, EDC).
- Expertise in clinical budgeting/resource allocation.
- Experience leading/mentoring diverse clinical teams and overseeing CROs.
- Excellent communication, leadership, and interpersonal skills.
- Strong organizational/time management; accountability, adaptability, attention to detail.
- Ability to work independently and collaboratively in a fast-paced, matrixed environment.
Benefits (as stated):
- Medical, dental, vision, supplemental disability insurance; relocation assistance may be available; annual bonus program; incentive stock option plan; 401k with flat non-elective employer contribution; HSA/FSA and supplemental plans; unlimited PTO; generous holiday schedule; stock options/RSUs/ESPP and target bonus.
Application Instructions:
- None provided.
- Drive global clinical operations strategy and execution for programs supporting IND-enabling through Phase 3 objectives and future clinical development plans.
- Collaborate cross-functionally with senior leadership to ensure operational initiatives align with company goals.
- Establish and refine scalable best practices to improve efficiency.
- Oversee development/review/implementation of study documents (protocols, informed consent forms, CRFs, monitoring plans, pharmacy manuals).
- Manage external partner relationships (CROs, central labs, patient advocacy groups) to ensure on-time, within-budget, quality deliverables.
- Provide program updates; establish KPIs/dashboards; present to study teams; represent Clinical Operations in internal/external meetings.
- Mentor and support direct reports; foster professional development and team culture.
- Oversee site strategy and relationships with investigators and key opinion leaders.
- Contribute to SOPs, work instructions, and operational plans to enhance compliance and efficiency.
- Develop operational plans, timelines, and budgets.
- Ensure all trial activities follow protocol, SOPs, GCP, and applicable regulations.
Required Education, Experience, Skills, and Abilities:
- Bachelor’s in life sciences or related field; 12+ years clinical research with 10+ years clinical trial management; advanced degree preferred.
- Strong experience in complex autoimmune indications; early phase preferred.
- Ability to define strategy and execute global clinical operations plans.
- Track record leading complex clinical programs start to completion.
- Strong knowledge of ICH-GCP and FDA/global regulatory guidelines.
- Proficiency with MS Office and clinical trial systems (CTMS, eTMF, EDC).
- Expertise in clinical budgeting/resource allocation.
- Experience leading/mentoring diverse clinical teams and overseeing CROs.
- Excellent communication, leadership, and interpersonal skills.
- Strong organizational/time management; accountability, adaptability, attention to detail.
- Ability to work independently and collaboratively in a fast-paced, matrixed environment.
Benefits (as stated):
- Medical, dental, vision, supplemental disability insurance; relocation assistance may be available; annual bonus program; incentive stock option plan; 401k with flat non-elective employer contribution; HSA/FSA and supplemental plans; unlimited PTO; generous holiday schedule; stock options/RSUs/ESPP and target bonus.
Application Instructions:
- None provided.