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Senior Director, Clinical Development Metabolism (MASH)

Merck
August 21, 2026
Full-time
Remote friendly (Rahway, NJ)
Worldwide
Clinical Research and Development
Role: Senior Director/Principal Scientist leading clinical research in Atherosclerosis & Metabolism, focusing on MASH (Metabolic Dysfunction-Associated Steatohepatitis) and obesity-related disorders. Objectives include developing and executing clinical trial strategies across all phases, managing study conduct, analyzing data for safety and efficacy, and supporting regulatory submissions and publications. Responsibilities encompass trial design, oversight of ongoing studies, translational work evaluation, and cross-functional collaboration with regulatory, manufacturing, and research teams. The role involves stakeholder engagement, external investigator collaboration, and scientific knowledge maintenance. Qualifications: MD or MD/PhD with 3+ years in industry or academia, proven clinical study oversight, and scientific achievement. Preferred: Board certification in Endocrinology, Gastroenterology, or Hepatology, with direct experience in Phase 2/3 trials for metabolic liver diseases. Skills include clinical development, trial management, biomedical research, and knowledge of metabolic and liver disorders. High-Value: Focus on metabolic liver disease, obesity, clinical trials (Phases 2-3), regulatory reporting, and external investigator engagement. Work setup: Travel ~25%, based in the US, with potential for flexible arrangements.