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Senior Director, Clinical Development

Revolution Medicines
September 01, 2026
Full-time
On-site
San Francisco Bay Area
Clinical Research and Development
Role: Senior Director, Clinical Science, supporting Revolution Medicines' clinical-stage oncology programs targeting RAS mutations. Responsibilities: lead clinical science strategies and documentation, oversee trial design and execution, and manage clinical data review and reporting; represent the clinical development plan across teams; mentor teams and collaborate with regulatory and scientific stakeholders. Requirements: PhD, PharmD, or equivalent; 10+ years in clinical development or related pharma R&D, with extensive expertise in oncology, particularly RAS pathway mutations; strong knowledge of GCP, ICH, FDA, EMA regulations; experience in trial design, protocol writing, and cross-functional coordination; proven regulatory engagement skills. Preferred: contributions to regulatory submissions, experience with major health authority interactions, leadership in clinical development strategy, and process improvements. High-Value: oncology, RAS mutations, G12C/G12D/G12V inhibitors, late-stage clinical development, regulatory submission experience, and cross-functional leadership. Work setup: likely onsite at Redwood City, CA, with competitive salary and benefits.