Senior Director, Clinical Development
Tango Therapeutics
September 02, 2026
Full-time
Remote friendly (Boston, MA)
Worldwide
Clinical Research and Development
Role: Senior Director of Clinical Development leading oncology programs at Tango Therapeutics, focusing on precision therapies for cancer. Responsibilities: drive clinical strategy from early-stage to registration, oversee study design and execution, serve as medical lead for trials, author key clinical documents, manage external Medical Monitors, collaborate with cross-functional teams (Regulatory, Biometrics, Data Management, etc.), and support regulatory submissions and interactions. Required qualifications: MD with board certification or eligibility in Medical Oncology or Hematology/Oncology, 5+ years in biotech/pharma clinical development, experience with targeted therapies, small molecules, or immuno-oncology agents, and experience with late-stage development and regulatory filings. Preferred skills: strong understanding of molecular biology, cancer genetics, immunology, and precision medicine; excellent leadership, communication, and strategic thinking abilities; proven ability to influence matrixed teams. High-value specifics: oncology, targeted therapies, immuno-oncology, early to late-stage development, regulatory submissions (INDs, NDAs, BLAs, MAAs). The role involves strategic leadership, external relationship management, and hands-on clinical oversight in a fast-paced biotech environment. Location: Boston; no travel details specified.