Senior Director Biostatistics
Verastem Oncology
June 25, 2026
Remote friendly (United States)
United States
Clinical Research and Development
Summary:
Senior member for Verastem Oncology biostatistics team; oversee statistical activities for multiple clinical studies, contribute to study design/protocol development, and analyze clinical trial data. Hands-on role with strategic initiatives, cross-functional technology development, and process improvement.
Responsibilities:
- Lead biostatistics efforts for multiple clinical studies; provide leadership to biostatistics/statistical programming teams
- Formulate, execute, and oversee statistical analyses; communicate results cross-functionally
- Lead biostatistics/programming aspects of regulatory submissions; independently respond to regulatory requests
- Author protocol statistical methods sections; review/edit endpoints, objectives, and assessments
- Create/oversee statistical analysis plans (SAPs) and ISS/ISEs; author/edit shells for tables, figures, listings
- Provide statistical input to IDMC/IRC charters, project management plan, and other study documents
- Create/manage timelines for SAPs, analysis specifications, and IDMC documents
- Conduct statistical modeling to support robust/efficient designs and address statistical issues
- Review CRF designs; review/approve SDTM/ADaM programming specs, pre-specified TLFs, and ad-hoc analyses
- Support safety/IDMC reviews
- Perform ad hoc/exploratory analyses
- Contribute to clinical study reports; author/interpret statistical sections
- Support publications and presentations
- Oversee CROs for outsourced statistical work; QC CRO results
Qualifications:
- PhD in statistics (8+ years clinical trial experience) or MS in statistics (11+ years)
- Knowledge of clinical trial statistical methods
- In-depth FDA, EMA, and ICH regulations/guidelines
- Experience with NDAs/MAAs is a plus
- Proficient in statistical programming (SAS required; R a plus)
- Experience with clinical trial design
- Strong communication, cross-functional collaboration, organization, analytical/problem-solving skills
- Positive, collaborative attitude
- Oncology clinical trial experience preferred
Benefits/Compensation:
- Base salary range: $250,000–$300,000; eligible for annual bonus, equity compensation, and competitive benefits package.
Senior member for Verastem Oncology biostatistics team; oversee statistical activities for multiple clinical studies, contribute to study design/protocol development, and analyze clinical trial data. Hands-on role with strategic initiatives, cross-functional technology development, and process improvement.
Responsibilities:
- Lead biostatistics efforts for multiple clinical studies; provide leadership to biostatistics/statistical programming teams
- Formulate, execute, and oversee statistical analyses; communicate results cross-functionally
- Lead biostatistics/programming aspects of regulatory submissions; independently respond to regulatory requests
- Author protocol statistical methods sections; review/edit endpoints, objectives, and assessments
- Create/oversee statistical analysis plans (SAPs) and ISS/ISEs; author/edit shells for tables, figures, listings
- Provide statistical input to IDMC/IRC charters, project management plan, and other study documents
- Create/manage timelines for SAPs, analysis specifications, and IDMC documents
- Conduct statistical modeling to support robust/efficient designs and address statistical issues
- Review CRF designs; review/approve SDTM/ADaM programming specs, pre-specified TLFs, and ad-hoc analyses
- Support safety/IDMC reviews
- Perform ad hoc/exploratory analyses
- Contribute to clinical study reports; author/interpret statistical sections
- Support publications and presentations
- Oversee CROs for outsourced statistical work; QC CRO results
Qualifications:
- PhD in statistics (8+ years clinical trial experience) or MS in statistics (11+ years)
- Knowledge of clinical trial statistical methods
- In-depth FDA, EMA, and ICH regulations/guidelines
- Experience with NDAs/MAAs is a plus
- Proficient in statistical programming (SAS required; R a plus)
- Experience with clinical trial design
- Strong communication, cross-functional collaboration, organization, analytical/problem-solving skills
- Positive, collaborative attitude
- Oncology clinical trial experience preferred
Benefits/Compensation:
- Base salary range: $250,000–$300,000; eligible for annual bonus, equity compensation, and competitive benefits package.