Senior Director Biostatistics

Role: Senior Director of Biostatistics at Madrigal Pharmaceuticals, leading biostatistical activities across all clinical development phases. Responsibilities include developing statistical strategies, overseeing complex analyses, contributing to protocol and regulatory document development, and collaborating cross-functionally with clinical, data management, and external CRO teams. The role also involves representing the company externally, mentoring junior staff, and supporting lifecycle management and regulatory submissions. Requirements: Ph.D. in Statistics or Biostatistics with 10+ years in pharma/biotech, proven experience supporting NDA submissions, expertise in advanced statistical methods, and regulatory knowledge. High-value: focus on metabolic liver disease (MASH), Phase 3 clinical trials, experience with FDA/EMA interactions, and leadership in biostatistics within a regulatory-driven environment. Work setup details are not specified.