Senior Clinical Trial Manager

Role: Lead clinical trial operations at Entrada Therapeutics, overseeing planning, execution, and closeout of multiple early-phase (Phase 1-2) genetic medicine studies for neuromuscular and retinal diseases, including DMD and DM1 programs. Responsibilities: manage CRO/vendor relationships, study setup, site and country selection, protocol development, data collection tools (eCRF), monitor trial progress, ensure compliance with ICH/GCP and global regulations (EU-CTR); oversee data reconciliation and quality; support training and budgeting; conduct site visits as needed. Requirements: BA/BS with 7+ years supporting independent clinical trial management; deep knowledge of GxP, global trial experience, strong communication skills, ability to travel ~20%; preference for candidates in the US, particularly New England. High-value: experience in gene/oligonucleotide therapies, early-stage clinical development, global/regulatory compliance, CRO oversight, and working in a fast-paced, collaborative environment.