Senior Clinical Trial Manager

Role: Senior Clinical Trial Manager leading global oncology Phase 2/3 clinical trials, primarily in NSCLC and colorectal cancer, with oversight of study execution from start-up to closeout. Responsibilities include site selection, feasibility, enrollment management, monitoring, issue escalation, risk-based quality oversight, data review, and regulatory compliance. The role involves managing CRO partnerships, ensuring inspection readiness, leading study documentation and audits, mentoring clinical operations staff, and driving continuous process improvements. Requirements: Bachelor's degree in life sciences or related field; 8-10+ years of clinical operations experience, including 7+ years managing international oncology trials in phases II-III; proficiency in GCP, ICH guidelines, and complex trial oversight; ability to interpret scientific data; strong leadership, negotiation, and organizational skills. Preferred qualifications include extensive trial management experience in sponsor settings, knowledge of drug development stages, and ability to travel up to 20%. High-value specifics: focus on immuno-oncology agents, late-stage trials, regulatory interactions, and cross-functional collaboration. Work setup: international travel required; location flexible within the US.