Senior Clinical Development (Medical Director), Dermatology

Role Summary

Senior Clinical Development Medical Director for Dermatology and Immunology, involved across the full scope of dermatology and autoimmune clinical drug development activities from discovery through first-in-human, proof of concept, and Phase 3 studies. Leads one or more studies within the portfolio and collaborates with cross-functional asset teams to advance clinical programs and asset strategy.

Responsibilities

• Broadly represent Alumis as a senior leader and spokesperson for Clinical Development within Dermatology and Immunology
• Provide leadership in the management and oversight of the global ESK-001 Phase 3 program in plaque psoriasis, leading one or more studies
• Contribute to cross-functional teams within Research, Biomarkers, Medical Affairs, Commercial, and Study Team as a Dermatology expert
• Support the clinical Science function in design and development of novel clinical studies and cross-functional initiatives
• Provide strategic support and implement clinical strategies across early and late-stage programs
• Coach, manage, inspire, and support team members to achieve business goals with entrepreneurial and collaborative mindset
• Maintain integrity and scientific standards in drug development
• Collaborate with CRO to provide medical monitoring oversight for the Phase 3 program
• Support planning and execution of publication plans, data generation, and submission activities

Qualifications

• MD or ex-US equivalent with board certification or eligibility in Dermatology or related immunology disease area with >5 years of drug development experience
• Strong communication skills with credibility to interface with Key Opinion Leaders, external health organizations, and regulators
• Ability to interact effectively in a cross-functional setting
• Strong interpersonal, influencing, presentation, and communication skills (written and verbal)
• Ability to assess and communicate expanding medical and scientific information and commercial dynamics impacting drug development
• Strong business acumen and ability to collaborate across functions
• Negotiation skills to influence without authority
• Proven track record of strategic, organizational, and executional skills across multiple activities and timelines
• Ability to work across diverse teams in a matrixed structure
• Organized, detail-oriented, and able to meet deadlines in a fast-paced environment
• Able to work autonomously and with high independence

Skills

• Cross-functional collaboration
• Clinical trial design and oversight
• Medical monitoring and data interpretation
• Scientific writing and publication planning
• Strategic program leadership
• Regulatory interface

Education

• MD or equivalent; board certification/eligibility in Dermatology or related immunology field

Additional Requirements

• Onsite presence required in South San Francisco, CA (onsite Tue–Thu); remote applicants considered with monthly onsite visit