Senior Clinical Development Medical Director
Exelixis
July 03, 2026
Remote friendly (United States)
United States
Clinical Research and Development
Summary/Job Purpose:
- Lead and execute early/late stage clinical trials for oncology products in development.
- Participate in design/planning of clinical studies and interpretation of study results.
- Establish and approve scientific methods for clinical protocols, data collection systems, and final reports.
- May recruit clinical investigators.
- Oversee adverse event reporting and safety monitoring; monitor protocol adherence and determine study completion.
Essential Duties and Responsibilities:
- Design, prepare, and initiate study protocols and required documentation in compliance with project plans, federal regulations, GCP, and good medical practice.
- Act as medical monitor for company-sponsored trials.
- Support project teams with therapeutic area–specific information.
- Collaborate with internal safety group to analyze and report safety data.
- Analyze and interpret clinical trial data; prepare reports for regulatory agencies and publication.
- Interact with key opinion leaders and investigators.
- Ensure consistency of scientific and development strategies for oncology products.
- Maintain high level of scientific/clinical knowledge in relevant disease area.
Education/Experience:
- MD (board certification/eligibility in Oncology or Hematology/Oncology desirable but not essential) required; minimum 8 years post-residency experience.
- Equivalent combination of education and experience.
Experience (Ideal):
- Drug development experience in biotech/pharma (or academia + industry; extensive academia alone may be considered).
- Hands-on experience designing, executing, and reporting controlled oncology clinical trials.
- Experience with molecular targeted or immunological therapies.
- Basic science knowledge relevant to clinical oncology (biochemistry, immunology, molecular biology and/or genetics).
Knowledge/Skills:
- Ability to work in cross-functional/matrix environment.
- Develop technical/business solutions to complex problems; identify/evaluate methods and procedures.
- Develop and maintain relationships with key opinion leaders.
- Strong interpersonal, influencing, presentation, and written/verbal communication skills.
- Strong organizational and time-management skills.
Job Complexity:
- In-depth evaluation of complex problems/data; independent judgment across functional areas.
- Regular interaction with executives and/or major customers.
- Lead and execute early/late stage clinical trials for oncology products in development.
- Participate in design/planning of clinical studies and interpretation of study results.
- Establish and approve scientific methods for clinical protocols, data collection systems, and final reports.
- May recruit clinical investigators.
- Oversee adverse event reporting and safety monitoring; monitor protocol adherence and determine study completion.
Essential Duties and Responsibilities:
- Design, prepare, and initiate study protocols and required documentation in compliance with project plans, federal regulations, GCP, and good medical practice.
- Act as medical monitor for company-sponsored trials.
- Support project teams with therapeutic area–specific information.
- Collaborate with internal safety group to analyze and report safety data.
- Analyze and interpret clinical trial data; prepare reports for regulatory agencies and publication.
- Interact with key opinion leaders and investigators.
- Ensure consistency of scientific and development strategies for oncology products.
- Maintain high level of scientific/clinical knowledge in relevant disease area.
Education/Experience:
- MD (board certification/eligibility in Oncology or Hematology/Oncology desirable but not essential) required; minimum 8 years post-residency experience.
- Equivalent combination of education and experience.
Experience (Ideal):
- Drug development experience in biotech/pharma (or academia + industry; extensive academia alone may be considered).
- Hands-on experience designing, executing, and reporting controlled oncology clinical trials.
- Experience with molecular targeted or immunological therapies.
- Basic science knowledge relevant to clinical oncology (biochemistry, immunology, molecular biology and/or genetics).
Knowledge/Skills:
- Ability to work in cross-functional/matrix environment.
- Develop technical/business solutions to complex problems; identify/evaluate methods and procedures.
- Develop and maintain relationships with key opinion leaders.
- Strong interpersonal, influencing, presentation, and written/verbal communication skills.
- Strong organizational and time-management skills.
Job Complexity:
- In-depth evaluation of complex problems/data; independent judgment across functional areas.
- Regular interaction with executives and/or major customers.