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Senior Business Systems Analyst

Ionis Pharmaceuticals, Inc.
Remote friendly (United States)
United States
$88,348 - $131,841 USD yearly
IT

Role Summary

We are seeking a Senior Business Systems Analyst to support the execution of business initiatives as part of the Global Product Strategy and Operations (GPSO) IT team. This cross-functional role is responsible for translating business needs into well-defined requirements, data specifications, and test artifacts that enable timely, compliant, and high-quality data delivery. This hands-on, execution-focused role centers on requirements management, data analysis and validation, testing, and day-to-day stakeholder coordination to ensure data readiness stays off the critical path for launches and ongoing operations.

Responsibilities

  • Business Requirements & Analysis
    • Partner with Market Access, Patient Services, Trade, and Commercial Ops stakeholders to translate business needs into clear system, data, reporting, and integration requirements.
    • Lead requirements gathering for new and evolving data feeds (e.g., specialty pharmacy, HUB, payer, copay, consent, claims, lab, trade and distribution partners).
    • Create and maintain BRDs, FRDs, user stories, acceptance criteria, workflows, and data mapping documents.
    • Challenge, validate and refine requirements to ensure solutions are scalable, feasible, and aligned with enterprise architecture.
  • Data Management & Quality
    • Partner with IT, Data Governance, and external vendors to enable intake, translate business needs into data requirements, define validation checks, and operational use of key data feeds, including:
      • HUB services data (referrals, benefits investigations, prior auth, enrollments).
      • Specialty pharmacy data (dispenses, inventory, patient status).
      • Payer/coverage data (formulary, restrictions, step edits, copay accumulators, rejections).
      • Trade & distribution data (3PL, wholesalers, chargebacks, returns, channel inventory).
    • Define data quality rules, perform root-cause analysis, and coordinate remediation with data aggregator, external vendors, and IT teams.
    • Manage metadata, data dictionaries, and lineage documentation.
  • Systems & Product Ownership Support
    • Work closely with IT engineering and architecture teams to support data platform and pipelines (e.g., Snowflake, Databricks, MDM).
    • Support design, testing and UAT for enhancements to dashboards, data models, and APIs.
    • Assist with vendor evaluations, SOW reviews, and ongoing solution performance monitoring.
    • Collaborate with IT teams supporting data warehouse, omnichannel, and reporting platforms to maintain integrated, high-quality data flows.
    • Participate in enterprise data governance councils and represent GPSO IT in cross-functional data working groups as needed.
  • Reporting & Analytics Enablement
    • Develop business logic for KPIs and metrics related to:
      • Patient journey oversight (referral โ†’ benefits check โ†’ PA โ†’ approval โ†’ dispense โ†’ adherence).
      • Payer coverage, affordability, and pull-through.
      • Specialty pharmacy operational performance.
      • Channel inventory, demand, and distribution flows.
    • Serve as a subject matter expert for visualization tools (Power BI).
    • Partner with analytics teams to ensure trust in insights and consistency in metric definitions.
    • Support ad-hoc reporting and dashboard enhancements as needed.
  • Stakeholder Management & Communication
    • Manage aligned stakeholder expectations across Market Access, Patient Services, Trade & Distribution, Finance, and Commercial Operations.
    • Communicate timelines, risks, data delays, and production issues clearly and professionally.
    • Facilitate cross-functional workshops to align on key data definitions and business processes.
    • Manage day-to-day coordination with business stakeholders, IT delivery teams, and data vendors.

Qualifications

Education & Experience

  • Bachelorโ€™s degree in information systems, data science, business, or related field; or equivalent work experience. Requires a minimum of 5 years of related experience with a bachelorโ€™s degree; or 3 years and a masterโ€™s degree.
  • 4โ€“8+ years of experience as a Business Analyst, Data Analyst, or similar role in pharma/biotech.
  • Experience supporting Market Access, Patient Services/HUB, or Trade & Distribution.

Technical Skills

  • Strong knowledge of:
    • Specialty pharmacy & HUB data flows
    • Payer and formulary data concepts
    • Trade/distribution data (3PL/wholesaler)
  • Familiarity with cloud data platforms (Snowflake, Databricks, Redshift, Azure, etc.).
  • Experience writing BRDs, user stories, and data mapping documents.
  • Understanding of APIs, batch processes, and data integration workflows.
  • Proficiency with reporting tools (Tableau, Power BI, Qlik).

Business & Functional Skills

  • Deep understanding of the patient access journey and specialty distribution model.
  • Ability to translate ambiguous business needs into precise technical requirements.
  • Strong problem-solving, data validation, and investigation skills.
  • Comfortable working in agile project environments.
  • Excellent communication and stakeholder-management skills.

Preferred Qualifications

  • Experience working with data vendors (e.g., McKesson, AmerisourceBergen, Cardinal, Lash Group, AssistRx, Inovalon, TrialCard/Agadia, etc.).
  • Background supporting commercial data ecosystems or platforms (MDM, CRM, data lakes).
  • Experience with privacy compliance considerations (PHI, HIPAA, de-identification).
  • Certification in Agile (CSM, PO), Business Analysis (CBAP), Six Sigma, ITIL or similar.
  • Hands-on experience with SQL (read/write basic to intermediate queries).
  • Experience with patient data tokenization
  • Experience with patient consent mastering
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