Ionis Pharmaceuticals, Inc. logo

Senior Business Systems Analyst

Ionis Pharmaceuticals, Inc.
Remote friendly (United States)
United States
$88,348 - $131,841 USD yearly
IT

Role Summary

Senior Business Systems Analyst to support the execution of business initiatives as part of the Global Product Strategy and Operations IT team. This cross-functional role translates business needs into requirements, data specifications, and test artifacts to enable timely, compliant, and high-quality data delivery. Partners with Data Management & Governance and Product/Technology leads to deliver scalable data solutions across Market Access, Patient Services, Trade & Distribution, Commercial Operations, and IT. Hands-on, execution-focused role focused on requirements management, data analysis and validation, testing, and stakeholder coordination to ensure data readiness for launches and ongoing operations.

Responsibilities

  • Business Requirements & Analysis: Partner with Market Access, Patient Services, Trade, and Commercial Ops stakeholders to translate business needs into clear system, data, reporting, and integration requirements.
  • Lead requirements gathering for new and evolving data feeds (e.g., specialty pharmacy, HUB, payer, copay, consent, claims, lab, trade and distribution partners).
  • Create and maintain BRDs, FRDs, user stories, acceptance criteria, workflows, and data mapping documents.
  • Challenge, validate and refine requirements to ensure solutions are scalable, feasible, and aligned with enterprise architecture.
  • Data Management & Quality: Partner with IT, Data Governance, and external vendors to enable intake, translate business needs into data requirements, define validation checks, and operational use of key data feeds, including:
    • HUB services data (referrals, benefits investigations, prior auth, enrollments).
    • Specialty pharmacy data (dispenses, inventory, patient status).
    • Payer/coverage data (formulary, restrictions, step edits, copay accumulators, rejections).
    • Trade & distribution data (3PL, wholesalers, chargebacks, returns, channel inventory).
  • Define data quality rules, perform root-cause analysis, and coordinate remediation with data aggregator, external vendors, and IT teams.
  • Manage metadata, data dictionaries, and lineage documentation.
  • Systems & Product Ownership Support: Work closely with IT engineering and architecture teams to support data platform and pipelines (e.g., Snowflake, Databricks, MDM).
  • Support design, testing and UAT for enhancements to dashboards, data models, and APIs.
  • Assist with vendor evaluations, SOW reviews, and ongoing solution performance monitoring.
  • Collaborate with IT teams supporting data warehouse, omnichannel, and reporting platforms to maintain integrated, high-quality data flows.
  • Participate in enterprise data governance councils and represent GPSO IT in cross-functional data working groups as needed.
  • Reporting & Analytics Enablement: Develop business logic for KPIs and metrics related to patient journey oversight, payer coverage/affordability/pull-through, specialty pharmacy operational performance, and channel inventory/demand/distribution flows.
  • Serve as a subject matter expert for visualization tools (Power BI).
  • Partner with analytics teams to ensure trust in insights and consistency in metric definitions.
  • Support ad-hoc reporting and dashboard enhancements as needed.
  • Stakeholder Management & Communication: Manage aligned stakeholder expectations across Market Access, Patient Services, Trade & Distribution, Finance, and Commercial Operations.
  • Communicate timelines, risks, data delays, and production issues clearly and professionally.
  • Facilitate cross-functional workshops to align on key data definitions and business processes.
  • Manage day-to-day coordination with business stakeholders, IT delivery teams, and data vendors.

Qualifications

  • Education & Experience (Required): Bachelorโ€™s degree in Information Systems, Data Science, Business, or related field with a minimum of 5 years of related experience; or 3 years with a masterโ€™s degree; or equivalent work experience. 4โ€“8+ years of experience as a Business Analyst, Data Analyst, or similar role in pharma/biotech. Experience supporting Market Access, Patient Services/HUB, or Trade & Distribution.
  • Technical Skills (Required): Strong knowledge of specialty pharmacy & HUB data flows; payer and formulary data concepts; trade/distribution data (3PL/wholesaler). Familiarity with cloud data platforms (Snowflake, Databricks, Redshift, Azure, etc.). Experience writing BRDs, user stories, and data mapping documents. Understanding of APIs, batch processes, and data integration workflows. Proficiency with reporting tools (Tableau, Power BI, Qlik).
  • Business & Functional Skills (Required): Deep understanding of the patient access journey and specialty distribution model. Ability to translate ambiguous business needs into precise technical requirements. Strong problem-solving, data validation, and investigation skills. Comfortable working in agile project environments. Excellent communication and stakeholder-management skills.
  • Preferred Qualifications: Experience working with data vendors (e.g., McKesson, AmerisourceBergen, Cardinal, Lash Group, AssistRx, Inovalon, TrialCard/Agadia). Background supporting commercial data ecosystems or platforms (MDM, CRM, data lakes). Experience with privacy compliance considerations (PHI, HIPAA, de-identification). Certification in Agile (CSM, PO), Business Analysis (CBAP), Six Sigma, ITLT or similar. Hands-on experience with SQL (read/write basic to intermediate queries). Experience with patient data tokenization and patient consent mastering.