Senior Biostatistician II
Vertex Pharmaceuticals
August 20, 2026
Remote friendly (Boston, MA)
United States
Clinical Research and Development
General Summary:
The Senior Biostatistician II will perform scientific statistical analyses in support of Global Medicines Development and Affairs, with guidance and mentoring on new and complex issues. The incumbent will complete assigned work in a resourceful manner and develop knowledge of related disciplines while applying a drug developer mindset.
Key Duties And Responsibilities:
- Design, develop, and execute statistical/technical infrastructure for clinical trials, observational studies, or real-world data (RWD) investigations.
- Participate in Study Execution Team (SET) meetings as the functional representative.
- Under supervision, author study Statistical Analysis Plans (SAPs), including TFL shells, and present to Statistical Review Forum (SRF).
- Plan and conduct cross-functional data review (xFDR), Key Results Memo (KRM), and Data Dissemination Plan (DDP).
- Collaborate with statistical programming and other functions to deliver high-quality TFLs; provide input to programming specifications and review.
- Develop statistical protocol sections, including sample size estimates and randomization plan.
- Contribute to clinical study reports (CSRs); may author/co-author publications and posters.
- Implement design and analysis methods; participate in SRF discussions for assigned studies.
- Contribute to departmental working groups on technical/operational issues.
Knowledge And Skills:
- Competence with SAS or R.
- Understanding of statistical methods used in drug development.
- Critical thinking and logical problem-solving.
- Excellent written/verbal communication; strong teamwork; collaborates well with non-statisticians.
Education And Experience:
- PhD or master’s in Statistics or Biostatistics.
- Typically 3 years of experience for master’s degree holders (or equivalent education/experience).
Pay Range:
- $132,200 - $198,200
The Senior Biostatistician II will perform scientific statistical analyses in support of Global Medicines Development and Affairs, with guidance and mentoring on new and complex issues. The incumbent will complete assigned work in a resourceful manner and develop knowledge of related disciplines while applying a drug developer mindset.
Key Duties And Responsibilities:
- Design, develop, and execute statistical/technical infrastructure for clinical trials, observational studies, or real-world data (RWD) investigations.
- Participate in Study Execution Team (SET) meetings as the functional representative.
- Under supervision, author study Statistical Analysis Plans (SAPs), including TFL shells, and present to Statistical Review Forum (SRF).
- Plan and conduct cross-functional data review (xFDR), Key Results Memo (KRM), and Data Dissemination Plan (DDP).
- Collaborate with statistical programming and other functions to deliver high-quality TFLs; provide input to programming specifications and review.
- Develop statistical protocol sections, including sample size estimates and randomization plan.
- Contribute to clinical study reports (CSRs); may author/co-author publications and posters.
- Implement design and analysis methods; participate in SRF discussions for assigned studies.
- Contribute to departmental working groups on technical/operational issues.
Knowledge And Skills:
- Competence with SAS or R.
- Understanding of statistical methods used in drug development.
- Critical thinking and logical problem-solving.
- Excellent written/verbal communication; strong teamwork; collaborates well with non-statisticians.
Education And Experience:
- PhD or master’s in Statistics or Biostatistics.
- Typically 3 years of experience for master’s degree holders (or equivalent education/experience).
Pay Range:
- $132,200 - $198,200