Senior Bioinformatics Scientist

Role: Senior Bioinformatics Scientist specializing in machine learning model development for Natera's methylation-based cancer detection assay in minimal residual disease (MRD) settings. Responsibilities: build, train, and evaluate algorithms; lead end-to-end research analyses; bridge wet-lab experimental design with computational analysis; ensure quality control across high-volume sequencing data; communicate findings to technical and cross-functional teams. Requirements: Ph.D. or Master’s in Bioinformatics, Computer Science, Engineering, Biochemistry, or related, with 0-3 or 4-6 years of experience respectively; expertise in genomics, sequencing data analysis, statistical methods, and machine learning (including neural networks, kernel methods, etc.); proficiency in Python, Linux, and familiarity with genomic databases such as TCGA, COSMIC, or OncoKB. High-Value: focus on cancer genomics, DNA methylation, liquid biopsy, oncology diagnostics, and assay development; collaborative environment involving computational and experimental scientists; position involves working with high-throughput sequencing data and developing models for cancer detection in clinical samples.