Senior Bioanalytical Scientist

Role Summary

Senior Bioanalytical Scientist

Responsibilities

• Method Development: Design and develop new assays from scratch. Optimize ligand binding assays (e.g. MSD, ELISA) with a focus on sensitivity, specificity, linearity, reproducibility and robustness. Independently troubleshoot assay performance issues and implement improvements. Write a detailed protocol of the methods developed to use in sample analysis.
• Data Analysis & Reporting: Document the experimental design and execution in ELN. Analyze experimental data using appropriate statistical tools. Prepare PowerPoint presentation and summarize results in technical reports, when needed. Present findings to internal teams and external stakeholders.
• Collaboration & Training: Work closely with cross-functional teams, including pharmacology and medicinal chemistry. Provide procedural training and mentorship to junior scientists. Support colleagues on sample analysis as the need arises.

Qualifications

• Ph.D in Biochemistry, Biology, Analytical Chemistry, or a related field with a minimum of 2-5 years of bioanalytical experience as a post-doctoral fellowship or scientist in biotech/pharma.
• Proficiency in troubleshooting and optimizing bioanalytical methods.
• Advanced knowledge and hands-on experience of ligand binding assay formats (e.g., ELISA, Solid).
• Previous experience developing bioanalytical assays (e.g. ELISA, MSD) for quantification of antisense oligonucleotides or siRNA is a plus
• Experience with bioanalytical instruments such as LC/MS is a plus
• Familiarity with bioanalytical method validation guidance (e.g. FDA, EMA, ICH M10)
• Experience with lab automation technologies.
• Strong technical writing skills for documentation and reporting.
• Proven ability to manage multiple projects simultaneously.
• Effective communication skills for presentations and team collaboration.