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Senior Associate Scientist, Obesity Muscle & Metabolism

Regeneron
3 months ago
On-site
Tarrytown, NY
Clinical Research and Development
Responsibilities:
- Support or lead in vivo studies in rodent models of obesity, insulin resistance, and muscle dysfunction, including compound dosing, tissue collection, and metabolic phenotyping.
- Conduct follow-up analysis of metabolic tissues using qPCR, western blotting, immunohistochemistry, and RNAScope.
- Design, execute, and troubleshoot in vitro experiments in primary and immortalized cell models of adipocytes and myotubes, including differentiation, stimulation, and compound testing.
- Analyze and interpret data using appropriate statistical methods; communicate findings in written reports and presentations.
- Maintain electronic lab notebooks, SOPs, and assay documentation to ensure data integrity and reproducibility.

Qualifications (to be considered):
- In vivo experience.
- BS or MS in Cell Biology, Physiology, Molecular Biology, Pharmacology, or related discipline.
- 3+ years of laboratory experience, preferably with mouse models.
- Experience designing/executing metabolic studies in rodent obesity models, including indirect calorimetry, glucose and insulin tolerance testing, assessing food intake, and body composition.
- Competence with data analysis/visualization tools (Excel, Prism, R, or Python) and understanding of experimental design and statistics.
- Excellent presentation, time management, and collaborative skills.

Preferred qualifications:
- Tissue culture, western blotting, ELISA, and flow cytometry in various cell lines.
- Histologic experience with metabolic tissues (liver, skeletal muscle, pancreas, brain).

Application instructions:
- Apply now.