Senior Associate Scientist, Investigative Sciences

Role: Senior Associate Scientist supporting RNAi mechanistic research in Alnylam's Investigative Sciences team, focusing on in vitro and in vivo studies of RNAi therapeutics. Responsibilities: conduct biochemical and cell/molecular biology assays, maintain and manipulate mammalian and primary cells, optimize siRNA delivery techniques, analyze data with software like GraphPad Prism and FlowJo, and present findings to cross-functional teams to inform drug design. Qualifications: BS/MS in Biology, Cell/Molecular Biology, or Biochemistry; 3-5 years of industry experience, especially with oligonucleotides; expertise in mammalian cell culture, molecular techniques (qPCR, ELISA), and fluorescence microscopy; strong independence, technical proficiency, and communication skills. HighValue: RNAi therapeutics, oligonucleotide field, in vitro and in vivo research, primary focus on gene silencing mechanisms, Cambridge MA location, onsite work, no travel specified.