Senior Associate Scientist

Role Summary

Senior Associate Scientist in the Genomics Medicine Unit, Cambridge, MA. You will execute in vivo studies to support the development of gene therapies and contribute to translation of preclinical programs across neurological, neuromuscular, immunology, ocular, rare blood, renal and metabolic diseases. This role involves collaborating with cross-functional teams to design, execute, and interpret studies that advance gene therapy programs.

Responsibilities

• Execute rodent pharmacology studies that evaluate gene therapy candidates
• Contribute to several experiments simultaneously and perform in a time sensitive manner
• Develop and carry out research involving various animal laboratory techniques including surgery, therapeutic administration, behavioral testing, and tissue / blood collection
• Communicate and coordinate with other scientists on the project team to draft, finalize, and implement study protocols. Follow protocols, standard operating procedures and independently execute tasks
• Collect and record data, prepare a summary of experimental procedures and results and present data in team meetings and across disease areas to support the Genomic Medicine Unit at large
• Act as an impactful contributor working in a team or as an individual member
• Foster creativity, productivity, execution with a sense of urgency, teamwork, accountability and cross-functional collaboration

Qualifications

• Required: MS in life science with a minimum of 3 years of experience or Required: BS in life science with a minimum of 6 years of experience in biotech / biopharma industry with hands-on working experience using research animals
• Required: Demonstrated experience and expertise in multiple delivery routes of administration into mice and rats as well as an understanding of behavioral analysis tools with mice and rats
• Preferred: Surgical experience with mice and rats and the willingness to learn multiple surgical delivery techniques, including stereotaxic delivery
• Preferred: Experience with in vivo ocular studies in rodent models including OCT imaging and ocular dosing procedures such as intravitreal delivery
• Required: Strong background experience with rodent tissue collection and tissue collection techniques
• Preferred: Experience designing pharmacological testing in various animal models with behavioral, biochemical and physiological endpoints
• Preferred: Demonstratable organizational skills and attention to detail
• Required: Ability to effectively communicate ideas, document and present research plus work in a collaborative environment