Senior Associate Scientist - Discovery Research, Regeneron Cell Medicines
Regeneron
June 25, 2026
On-site
Cambridge, MA
Clinical Research and Development
As a Senior Associate Scientist, typical day responsibilities include:
- Contribute to preclinical research and development of CAR/TCR T cell therapies in solid tumor indications.
- Characterize genetically modified primary human T cells via immunophenotyping using multi-color flow cytometry and molecular assays (PCR, library preps for NGS, RNA-Seq).
- Develop and perform immunological functional assays to assess immune cell activation, anti-tumor cytotoxicity, proliferation, and cytokine secretion to evaluate CAR/TCR T-cell therapeutic efficacy.
- Design experiments independently and contribute to project direction.
- Maintain an electronic lab notebook and document experiment results.
- Review and present research data to the functional team.
This role may be a fit if you:
- Have a can-do attitude, are curious, and excel in creative problem solving.
- Can multi-task, manage time well, and adapt quickly to new research areas and techniques independently.
- Are scientifically rigorous, highly organized, and a self-starter with strong attention to detail.
- Have strong verbal and written communication skills.
Qualifications/requirements:
- BS/MS in immunology, cell biology, or related field; 3+ years of relevant experience.
- Experience working in a biotech/pharmaceutical industry.
- Strong understanding of immunology and cancer biology.
- Extensive experience isolating primary human immune cells and mammalian cell culture, including primary human T lymphocytes.
- Experience with in-vitro immunological studies and functional T-cell assays using multi-color flow cytometry, ELISA, and cytotoxicity assays.
- Gene delivery into T cells or tumor cells (lentiviral vector transduction, CRISPR/Cas9 editing, and mRNA electroporation) is a plus.
- Molecular biology techniques (PCR, qPCR, Westerns, NGS/RNA-Seq library preps) are advantageous.
Application instructions:
- Apply now.
- Contribute to preclinical research and development of CAR/TCR T cell therapies in solid tumor indications.
- Characterize genetically modified primary human T cells via immunophenotyping using multi-color flow cytometry and molecular assays (PCR, library preps for NGS, RNA-Seq).
- Develop and perform immunological functional assays to assess immune cell activation, anti-tumor cytotoxicity, proliferation, and cytokine secretion to evaluate CAR/TCR T-cell therapeutic efficacy.
- Design experiments independently and contribute to project direction.
- Maintain an electronic lab notebook and document experiment results.
- Review and present research data to the functional team.
This role may be a fit if you:
- Have a can-do attitude, are curious, and excel in creative problem solving.
- Can multi-task, manage time well, and adapt quickly to new research areas and techniques independently.
- Are scientifically rigorous, highly organized, and a self-starter with strong attention to detail.
- Have strong verbal and written communication skills.
Qualifications/requirements:
- BS/MS in immunology, cell biology, or related field; 3+ years of relevant experience.
- Experience working in a biotech/pharmaceutical industry.
- Strong understanding of immunology and cancer biology.
- Extensive experience isolating primary human immune cells and mammalian cell culture, including primary human T lymphocytes.
- Experience with in-vitro immunological studies and functional T-cell assays using multi-color flow cytometry, ELISA, and cytotoxicity assays.
- Gene delivery into T cells or tumor cells (lentiviral vector transduction, CRISPR/Cas9 editing, and mRNA electroporation) is a plus.
- Molecular biology techniques (PCR, qPCR, Westerns, NGS/RNA-Seq library preps) are advantageous.
Application instructions:
- Apply now.