Senior Associate Scientist, Cellular Genomics
Pfizer
August 24, 2026
On-site
Cambridge, MA
Clinical Research and Development
Role Responsibilities:
- Perform upstream data processing, quality assessment, and troubleshooting of sequencing runs, metadata, libraries, and genomic datasets.
- Use computational biology/bioinformatics workflows (including AI-enabled tools as appropriate) for quality assessment, biological interpretation, and reproducible reporting.
- Generate and document analytical outputs (QC summaries, exploratory analyses, figures/tables, concise technical summaries).
- Support experimental design/data management discussions and interpretation of genomic readouts.
- Evaluate/benchmark/qualify new or improved workflows, assays, platforms, instrumentation, and analytical approaches; document results.
- Execute a wet-lab component: sample preparation, tissue dissociation, cell/nuclei isolation, nucleic acid extraction, library prep, QC, sequencing, and data generation.
- Onboard/train scientists on genomics workflows and documentation best practices; contribute to technical updates.
- Stay current with single-cell, spatial transcriptomics, multiomics, reproducible bioinformatics, and agentic computational biology.
- Draft/maintain analysis and experimental plans, validation reports, work instructions/SOPs; maintain compliant electronic lab notebooks.
Qualifications (Required):
- Bachelor’s (0–3 yrs) or Master’s (0+ yrs) in relevant fields.
- Experience with genomics analysis/QC/visualization/reproducible workflows (bulk RNA-seq, sc/snRNA-seq, spatial, targeted/immune repertoire/epigenomics, or related).
- Python, R, command-line tools, notebooks, and/or version-controlled workflows.
- Foundational hands-on molecular biology/genomics wet-lab experience.
Preferred:
- AI-enabled/agentic bioinformatics tools; inflammation/immunology/neuro-inflammation/translational medicine expertise.
Benefits:
- Base salary: $68,600–$114,300; bonus target 7.5% (Global Performance Plan). 401(k) with match, additional retirement contribution, paid vacation/holidays/personal days, caregiver/parental and medical leave, and medical/prescription/dental/vision.
Application instructions:
- Work location: On premise. Last day to apply: September 7, 2026.
- Perform upstream data processing, quality assessment, and troubleshooting of sequencing runs, metadata, libraries, and genomic datasets.
- Use computational biology/bioinformatics workflows (including AI-enabled tools as appropriate) for quality assessment, biological interpretation, and reproducible reporting.
- Generate and document analytical outputs (QC summaries, exploratory analyses, figures/tables, concise technical summaries).
- Support experimental design/data management discussions and interpretation of genomic readouts.
- Evaluate/benchmark/qualify new or improved workflows, assays, platforms, instrumentation, and analytical approaches; document results.
- Execute a wet-lab component: sample preparation, tissue dissociation, cell/nuclei isolation, nucleic acid extraction, library prep, QC, sequencing, and data generation.
- Onboard/train scientists on genomics workflows and documentation best practices; contribute to technical updates.
- Stay current with single-cell, spatial transcriptomics, multiomics, reproducible bioinformatics, and agentic computational biology.
- Draft/maintain analysis and experimental plans, validation reports, work instructions/SOPs; maintain compliant electronic lab notebooks.
Qualifications (Required):
- Bachelor’s (0–3 yrs) or Master’s (0+ yrs) in relevant fields.
- Experience with genomics analysis/QC/visualization/reproducible workflows (bulk RNA-seq, sc/snRNA-seq, spatial, targeted/immune repertoire/epigenomics, or related).
- Python, R, command-line tools, notebooks, and/or version-controlled workflows.
- Foundational hands-on molecular biology/genomics wet-lab experience.
Preferred:
- AI-enabled/agentic bioinformatics tools; inflammation/immunology/neuro-inflammation/translational medicine expertise.
Benefits:
- Base salary: $68,600–$114,300; bonus target 7.5% (Global Performance Plan). 401(k) with match, additional retirement contribution, paid vacation/holidays/personal days, caregiver/parental and medical leave, and medical/prescription/dental/vision.
Application instructions:
- Work location: On premise. Last day to apply: September 7, 2026.