Senior Associate Scientist, Biology
Alnylam Pharmaceuticals
August 15, 2026
On-site
Cambridge, MA
Clinical Research and Development
Key Responsibilities
- Contribute to study design and execution to characterize molecules for RNAi therapeutic programs, including rodent metabolic disease models
- Develop and conduct assays such as qPCR, western blot, and ELISA to support in vivo studies
- Perform in vitro and cell-based assays to characterize drug activity
- Perform in vivo procedures in rodents, including administration of therapeutics via established methodologies
- Analyze and interpret data
- Prepare experimental reports and data presentations
- Prepare SOPs/protocols
- Present data to internal and external groups
Qualifications
- Minimum B.S. in a life sciences-related discipline (e.g., Molecular Biology, Cell Biology, Genetics) with 4+ years of laboratory research, or M.S. with 2+ years of laboratory research
- Proficiency in RNA/DNA/protein analysis techniques, including ELISA, western blotting, and qPCR
- Cell/tissue culture experience
- Basic rodent in vivo skills (animal handling, subcutaneous/intravenous dosing, blood collection, necropsy/dissection) highly desired
- Experience running obese rodent disease models highly desired
- Ability to perform and troubleshoot assays independently or with limited direction
- Strong experimental design knowledge; ability to analyze results, propose future directions, and generate clear reports
- Flexible, open to new tasks, and able to work on tight deadlines
- Proven team collaboration ability
- Cover letter encouraged
Location/Work Setting
- Onsite; primarily located in Cambridge, MA
- Contribute to study design and execution to characterize molecules for RNAi therapeutic programs, including rodent metabolic disease models
- Develop and conduct assays such as qPCR, western blot, and ELISA to support in vivo studies
- Perform in vitro and cell-based assays to characterize drug activity
- Perform in vivo procedures in rodents, including administration of therapeutics via established methodologies
- Analyze and interpret data
- Prepare experimental reports and data presentations
- Prepare SOPs/protocols
- Present data to internal and external groups
Qualifications
- Minimum B.S. in a life sciences-related discipline (e.g., Molecular Biology, Cell Biology, Genetics) with 4+ years of laboratory research, or M.S. with 2+ years of laboratory research
- Proficiency in RNA/DNA/protein analysis techniques, including ELISA, western blotting, and qPCR
- Cell/tissue culture experience
- Basic rodent in vivo skills (animal handling, subcutaneous/intravenous dosing, blood collection, necropsy/dissection) highly desired
- Experience running obese rodent disease models highly desired
- Ability to perform and troubleshoot assays independently or with limited direction
- Strong experimental design knowledge; ability to analyze results, propose future directions, and generate clear reports
- Flexible, open to new tasks, and able to work on tight deadlines
- Proven team collaboration ability
- Cover letter encouraged
Location/Work Setting
- Onsite; primarily located in Cambridge, MA