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Senior Associate Scientist, Bioinformatics

Alnylam Pharmaceuticals
Full-time
Remote friendly (Cambridge, MA)
United States
$76,300 - $114,500 USD yearly
Clinical Research and Development

Role Summary

Senior Associate Scientist, Bioinformatics. Role focuses on analyzing and communicating results from large NGS datasets, developing and evaluating sequencing pipelines, and contributing to a bioinformatics team within a RNAi therapeutics company.

Responsibilities

  • Run and develop proprietary Next Generation Sequencing analysis pipelines for short- and long-read technologies.
  • Communicate results of computational analyses to interdisciplinary teams of scientists.
  • Investigate state-of-the-art statistical methods and omics tools for novel sequencing technologies (e.g., RNA modification measures, proteogenomics).
  • Assist in the interpretation of results from complex scientific experiments.
  • Professionally maintain code in a version-controlled repository.
  • Contribute to our data science culture.

Qualifications

  • M.S. in a quantitative discipline, or B.S. with 2+ years of equivalent professional experience.
  • Coding capability in R and Python.
  • Prior experience with the analysis of omics-based biological datasets; familiarity with NGS and differential expression analysis tools preferred.
  • Experience with statistical methods and comfort reading and understanding scientific publications is preferred.
  • Drive to learn and understand new sequencing-based technologies, and to develop and troubleshoot downstream analysis pipelines.
  • Comfort working with Unix systems and cloud-based computing environments and tools (e.g., AWS, Docker).
  • Knowledge of, or interest in learning, the fundamentals of RNAi biology.
  • Experience communicating and presenting scientific results, and collaborating with colleagues with varied skill sets.

Skills

  • Bioinformatics analysis
  • NGS data processing
  • Statistical methods
  • Programming in R and Python
  • Version control and collaboration

Education

  • M.S. in a quantitative discipline, or B.S. with relevant experience as listed in Qualifications
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