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Role Summary
Senior Associate Scientist to join the Bioassay team in the Therapeutic Proteins Department. Develop cell-based functional assays to identify and characterize therapeutic antibodies. Collaborate across functions to meet project achievements and deliver therapies that transform patients' lives.
Responsibilities
- Culturing mammalian cells and engineering cell lines via transfection, transduction and CRISPR
- Characterizing cells and reagents by flow cytometry, immunocytochemistry and immunoblotting
- Developing cell-based bioassays and using them to screen antibodies in 96-well and 384-well plate formats
- Analyzing data and troubleshooting experiments
- Maintaining accurate and reliable records including electronic notebooks and all other pertinent documentation
- Presenting data in small and large group settings
Qualifications
- Required: BS/MS with a minimum of 3-5+ years of relevant experience
- Required: Experience with mammalian cell culture, cell engineering and validation, and cell-based assay development
- Preferred: Experience with flow cytometry
- Required: Ability to work collaboratively, multi-task with attention to details, and communicate well
- Preferred: Experience with high throughput assays, therapeutic antibody development, primary immune cell assays and effector function assays
- Must be comfortable working on multiple projects at once and meeting tight deadlines
Skills
- Laboratory-based role with strong skill and career development orientation
- Detail-oriented with strong organizational and time-management skills
- Excellent verbal and written communication skills
Education
- BS or MS degree with relevant experience as specified above