Scientist - RNA Sciences & Preclinical Manufacturing
Bristol Myers Squibb
August 21, 2026
Remote friendly (Cambridge, MA)
United States
Operations
Position Summary
Scientist on the RNA Sciences and Preclinical Manufacturing team, interfacing RNA/DNA research, process development, and preclinical material production to support in vivo studies, platform development, and technology maturation.
Position Responsibilities
- Develop and execute bench-scale manufacturing processes for preclinical-grade DNA and mRNA across diverse construct formats to meet quality, yield, and timeline needs.
- Support manufacturing via DNA molecular cloning, cell-based or cell-free DNA template production, and DNA purification.
- Produce mRNA and circRNA using in vitro transcription and bench-scale purification.
- Partner with analytical and process development groups to improve production, purification, and quality assessment methods.
- Perform additional molecular biology/downstream/analytical workflows as needed (e.g., sequencing and amplification-based methods to assess nucleic acid identity, abundance, and integrity).
- Coordinate production prioritization, maintain inventory records, and procure reagents.
- Collaborate across RNA Sciences, Discovery Biology, and partner teams to accelerate programs.
Experience / Qualifications
Basic Qualifications:
- Bachelor’s degree with 5+ years academic/industry experience; or Master’s with 3+ years; or Ph.D./equivalent in Life Sciences.
Preferred Qualifications:
- B.S./M.S. in Biology/Biochemistry/Molecular Biology (4+ years) or Ph.D. (0–1 years).
- Hands-on plasmid DNA production and in vitro transcription of mRNA/circRNA (required).
- Experience troubleshooting plasmid DNA workflows (highly desirable).
- Analytical experience: chromatographic separation, CGE, qPCR, or sequencing (highly desirable).
- Experience with automated liquid handlers (plus).
Benefits (explicitly listed)
- Health coverage (medical/pharmacy/dental/vision), wellbeing support, 401(k), disability and life insurance, and related protections.
- Paid time off (flexible time off for US exempt employees; specified vacation/holiday structure for Phoenix/PR/Rayzebio roles).
Application instructions
- If the role interests you but doesn’t perfectly match your resume, apply anyway.
Scientist on the RNA Sciences and Preclinical Manufacturing team, interfacing RNA/DNA research, process development, and preclinical material production to support in vivo studies, platform development, and technology maturation.
Position Responsibilities
- Develop and execute bench-scale manufacturing processes for preclinical-grade DNA and mRNA across diverse construct formats to meet quality, yield, and timeline needs.
- Support manufacturing via DNA molecular cloning, cell-based or cell-free DNA template production, and DNA purification.
- Produce mRNA and circRNA using in vitro transcription and bench-scale purification.
- Partner with analytical and process development groups to improve production, purification, and quality assessment methods.
- Perform additional molecular biology/downstream/analytical workflows as needed (e.g., sequencing and amplification-based methods to assess nucleic acid identity, abundance, and integrity).
- Coordinate production prioritization, maintain inventory records, and procure reagents.
- Collaborate across RNA Sciences, Discovery Biology, and partner teams to accelerate programs.
Experience / Qualifications
Basic Qualifications:
- Bachelor’s degree with 5+ years academic/industry experience; or Master’s with 3+ years; or Ph.D./equivalent in Life Sciences.
Preferred Qualifications:
- B.S./M.S. in Biology/Biochemistry/Molecular Biology (4+ years) or Ph.D. (0–1 years).
- Hands-on plasmid DNA production and in vitro transcription of mRNA/circRNA (required).
- Experience troubleshooting plasmid DNA workflows (highly desirable).
- Analytical experience: chromatographic separation, CGE, qPCR, or sequencing (highly desirable).
- Experience with automated liquid handlers (plus).
Benefits (explicitly listed)
- Health coverage (medical/pharmacy/dental/vision), wellbeing support, 401(k), disability and life insurance, and related protections.
- Paid time off (flexible time off for US exempt employees; specified vacation/holiday structure for Phoenix/PR/Rayzebio roles).
Application instructions
- If the role interests you but doesn’t perfectly match your resume, apply anyway.