Scientist, Process Sciences

Overview:

The Scientist, Process Sciences will be responsible for development, characterization and scale-up of biocatalytic processes. The successful candidate will work closely with cross-functional teams and contract manufacturing organizations on process development, process transfer, and oversight of oligonucleotide drug candidate manufacturing.

This position is onsite and will be located at our Kendall Square offices in Cambridge, MA.

Key Responsibilities:

• Contribute to process development, optimization, and scale-up of biocatalytic processes.
• Support the process and product characterization of small molecules and oligonucleotide APIs.
• Contribute to the management and optimization of in-house and contract manufacturing processes.
• Author and review technical protocols and development reports in support of manufacturing and process characterization activities.
• Author, edit, and review manufacturing documentation according to regulatory and procedural guidelines.
• Work closely with analytical development, manufacturing, QA, QC and CMO/CRO on the process transfer and process optimization.
• Contribute to strategic technical discussions and presenting progress at internal and external scientific meetings.

Qualifications:

• Ph.D. in chemistry, chemical engineering, or biochemical engineering.
• Process research and development experience in applied biocatalysis.
• Demonstrated proficiency in the design and development of practical processes for manufacture of small molecules and oligonucleotides.
• Hands-on experience in process development and analytical methods for process and product characterization.
• Excellent organizational and communication skills.
• Demonstrated strong operational execution and problem-solving skills.
• Desire to work in a fast-paced, deadline-driven environment.

About Alnylam:

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Our culture: Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we’ve been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2023 for the third consecutive year, one of Science Magazine’s Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK – among others.