Scientist, Preclinical Operations

Role Summary

We are seeking a Scientist, Preclinical Operations to join our experienced drug discovery and development team and help advance our gastrointestinal (GI) and cardiorenal research programs. The successful candidate will contribute to the development of GI/cardiorenal translational and biomarker strategies and provide scientific support across multiple drug programs. A key component of this role will be coordinating and monitoring work conducted by contract research organizations (CROs), with a focus on evaluating drug targets and mechanisms involved in GI and cardiorenal pathophysiology in support of the company’s discovery and development efforts.

Responsibilities

• Identify, establish and manage collaborations with CROs and academic institutions and key opinion leaders in relevant disease areas for research projects
• Assist with the development and execution, through CROs, relevant in vivo models critical for evaluating compound activity, mechanism of action, and generation of key data sets that drive drug programs
• Review, analyze, and summarize data; prepare high-quality presentations for internal discussions
• Support drug discovery efforts, including scientific due diligence and preclinical de-risking of GI/cardiorenal opportunities
• Collaborate with drug development teams to generate IND-enabling data
• Track project resources and invoices
• Author scientific reports and supporting documentation for IND submissions

Qualifications

• Required: Ph.D. in biology, pharmacology, or related discipline with 2 - 5 years of related experience or equivalent experience
• Required: Experience outsourcing work to CROs located in the US or abroad
• Preferred: Prior experience in the pharmaceutical or biotechnology industry preferred
• Preferred: Experience or knowledge in gut physiology, including the role of intestinal receptors and transporters, is desirable
• Required: Strong commitment to high-quality research and timely, organized execution of research plans
• Required: Excellent written and verbal communication skills, with the ability to collaborate effectively in a dynamic, cross-functional team environment

Education

• Ph.D. in biology, pharmacology, or related discipline