Scientist, Pharmacokinetics
Merck
September 03, 2026
Full-time
On-site
South San Francisco, CA
Clinical Research and Development
Role: Support preclinical drug discovery within the DMPK group by characterizing ADME properties of biologics and conjugates across therapeutic areas such as immunology, oncology, cardiovascular, and ophthalmology. Responsibilities: conduct in vitro/ex vivo assays, operate LC-MS/MS bioanalytical methods, interpret data to inform pipeline decisions, and contribute to scientific initiatives. Requirements: Bachelor's or Masterβs in analytical sciences, biochemistry, biology, or related fields; 3+ yearsβ experience with mammalian cell culture, cell-based assays, and LC-MS/MS bioanalysis; proficiency with biological matrices and assay development. Preferred: experience with protein characterization, flow cytometry, automated assays, or PK/ADME concepts; published research record and proficiency with data analysis tools. HighValue: biologics, conjugates, cell-based assays, LC-MS/MS bioanalysis, ADME characterization, preclinical drug discovery, collaborations within multidisciplinary teams. WorkSetup: on-site in South San Francisco; travel not required.