Scientist, Membrane Protein Biochemistry
Amgen
August 08, 2026
On-site
South San Francisco, CA
Clinical Research and Development
Scientist, Membrane Protein Biochemistry
What You Will Do
- Design strategies for recombinant production of polytopic membrane protein (MP) targets and purify MPs into stable formulations with detailed analytical characterization.
- Develop capabilities to increase success rates of large-molecule and small-molecule therapeutic discovery programs.
- Onsite laboratory position at South San Francisco site.
Key Responsibilities
- Independently devise and implement state-of-the-art membrane protein production strategies; conduct experiments with rigorous documentation and quality-focused deliverables.
- Analyze and interpret scientific data and communicate results to diverse scientific audiences.
- Collaborate with other scientists to plan methodological approaches, resources, timelines, and milestones.
- Stay current in membrane protein expertise to advise supervisors and colleagues on future technology development strategies.
Basic Qualifications
- Ph.D. in Biochemistry, Biophysics, Chemistry, Molecular Biology, or related discipline
OR Master’s degree + 2 years relevant laboratory experience
OR Bachelor’s degree + 4 years relevant laboratory experience
Preferred Qualifications
- Ph.D. plus 0–2 years relevant postdoctoral experience
- Independent experimental design/execution/interpretation; solid publication record with first-author publications
- Proven expertise with ÄKTA systems and analytical methods (e.g., HPLC/UPLC SEC/fSEC, spectroscopy, mass spectrometry)
- Structural biology or MP molecular pharmacology expertise (plus)
- Excellent written/oral communication, leadership, and teamwork in a fast-paced environment
Benefits (if applicable per posting)
- Retirement and Savings Plan, medical/dental/vision, life/disability insurance, flexible spending accounts; discretionary annual bonus; stock-based long-term incentives; time-off plans; flexible work models where possible.
Application Instructions
- Apply via careers.amgen.com. No application deadline; applications accepted until a sufficient number are received or a candidate is selected. Sponsorship not guaranteed.
What You Will Do
- Design strategies for recombinant production of polytopic membrane protein (MP) targets and purify MPs into stable formulations with detailed analytical characterization.
- Develop capabilities to increase success rates of large-molecule and small-molecule therapeutic discovery programs.
- Onsite laboratory position at South San Francisco site.
Key Responsibilities
- Independently devise and implement state-of-the-art membrane protein production strategies; conduct experiments with rigorous documentation and quality-focused deliverables.
- Analyze and interpret scientific data and communicate results to diverse scientific audiences.
- Collaborate with other scientists to plan methodological approaches, resources, timelines, and milestones.
- Stay current in membrane protein expertise to advise supervisors and colleagues on future technology development strategies.
Basic Qualifications
- Ph.D. in Biochemistry, Biophysics, Chemistry, Molecular Biology, or related discipline
OR Master’s degree + 2 years relevant laboratory experience
OR Bachelor’s degree + 4 years relevant laboratory experience
Preferred Qualifications
- Ph.D. plus 0–2 years relevant postdoctoral experience
- Independent experimental design/execution/interpretation; solid publication record with first-author publications
- Proven expertise with ÄKTA systems and analytical methods (e.g., HPLC/UPLC SEC/fSEC, spectroscopy, mass spectrometry)
- Structural biology or MP molecular pharmacology expertise (plus)
- Excellent written/oral communication, leadership, and teamwork in a fast-paced environment
Benefits (if applicable per posting)
- Retirement and Savings Plan, medical/dental/vision, life/disability insurance, flexible spending accounts; discretionary annual bonus; stock-based long-term incentives; time-off plans; flexible work models where possible.
Application Instructions
- Apply via careers.amgen.com. No application deadline; applications accepted until a sufficient number are received or a candidate is selected. Sponsorship not guaranteed.