Scientist, Membrane Protein Biochemistry
Amgen
June 26, 2026
On-site
South San Francisco, CA
Clinical Research and Development
Scientist, Membrane Protein Biochemistry
What You Will Do
- Design strategies for recombinant production of polytopic membrane protein (MP) targets and purify MPs into stable formulations with detailed analytical characterization.
- Develop capabilities to increase success rates of large-molecule and small-molecule therapeutic discovery programs.
- Onsite laboratory position at the South San Francisco site.
Key Responsibilities
- Independently devise and implement state-of-the-art membrane protein production strategies using laboratory experiments with rigorous documentation and quality-focused deliverables.
- Analyze and interpret scientific data and communicate results to diverse scientific audiences.
- Collaborate with other scientists to plan methodological approaches, resources, timelines, and milestones.
- Stay current in membrane protein expertise to advise supervisors and colleagues on future technology development strategies.
Basic Qualifications
- Ph.D. in Biochemistry, Biophysics, Chemistry, Molecular Biology, or a related discipline
OR
- Master’s degree and 2 years of relevant laboratory experience
OR
- Bachelor’s degree and 4 years of relevant laboratory experience
Preferred Qualifications
- Ph.D. plus 0–2 years of relevant postdoctoral experience
- Independent experimental design/execution/interpretation with first-author publication(s)
- Expertise with ÄKTA systems and analytical methods for MP characterization (HPLC/UPLC (SEC, fSEC), spectroscopy, mass spectrometry)
- Expertise in structural biology or MP molecular pharmacology (plus)
- Excellent written/oral communication, leadership, and teamwork in a fast-paced environment
Benefits (as stated)
- Total Rewards Plan with health and welfare plans, retirement/savings contributions, life/disability insurance, flexible spending accounts, bonus/incentives (role-dependent), stock-based incentives, time-off plans, and flexible work models where possible.
Application Instructions
- Apply at careers.amgen.com. No application deadline; applications continue until sufficient candidates are received or a candidate is selected.
What You Will Do
- Design strategies for recombinant production of polytopic membrane protein (MP) targets and purify MPs into stable formulations with detailed analytical characterization.
- Develop capabilities to increase success rates of large-molecule and small-molecule therapeutic discovery programs.
- Onsite laboratory position at the South San Francisco site.
Key Responsibilities
- Independently devise and implement state-of-the-art membrane protein production strategies using laboratory experiments with rigorous documentation and quality-focused deliverables.
- Analyze and interpret scientific data and communicate results to diverse scientific audiences.
- Collaborate with other scientists to plan methodological approaches, resources, timelines, and milestones.
- Stay current in membrane protein expertise to advise supervisors and colleagues on future technology development strategies.
Basic Qualifications
- Ph.D. in Biochemistry, Biophysics, Chemistry, Molecular Biology, or a related discipline
OR
- Master’s degree and 2 years of relevant laboratory experience
OR
- Bachelor’s degree and 4 years of relevant laboratory experience
Preferred Qualifications
- Ph.D. plus 0–2 years of relevant postdoctoral experience
- Independent experimental design/execution/interpretation with first-author publication(s)
- Expertise with ÄKTA systems and analytical methods for MP characterization (HPLC/UPLC (SEC, fSEC), spectroscopy, mass spectrometry)
- Expertise in structural biology or MP molecular pharmacology (plus)
- Excellent written/oral communication, leadership, and teamwork in a fast-paced environment
Benefits (as stated)
- Total Rewards Plan with health and welfare plans, retirement/savings contributions, life/disability insurance, flexible spending accounts, bonus/incentives (role-dependent), stock-based incentives, time-off plans, and flexible work models where possible.
Application Instructions
- Apply at careers.amgen.com. No application deadline; applications continue until sufficient candidates are received or a candidate is selected.