Scientist - Medicinal Chemistry

Role: Medicinal Chemistry Scientist focused on designing, synthesizing, and purifying novel compounds for clinical drug development within Amgen's Oncology, Inflammation, General Medicine, and Rare Disease areas. Responsibilities include developing synthetic routes, troubleshooting high-level organic reactions, and contributing to structure-activity relationship studies; also involve structural analysis using NMR and mass spectrometry, and preparing data for publications and patent applications. Qualifications: PhD or equivalent experience (Master's with 2+ years or Bachelor's with 4+ years of lab experience); demonstrated ability in synthetic organic chemistry, structural analysis, and laboratory practices. Preferred: peer-reviewed publications, strong troubleshooting skills, and leadership qualities. High-value specifics: Onsite at Thousand Oaks, CA; focus on innovative approaches such as PROTAC within Amgen’s Induced Proximity Platform; contribution to preclinical and early development stages; GxP lab environment; collaborative cross-functional interactions. Work setup includes a lab-based, onsite position with emphasis on safety, technical expertise, and communication skills.