Scientist, LNP Process and Development
Flagship Pioneering
September 29, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Operations
Role: Support development and scale-up of lipid nanoparticle (LNP) formulations for nucleic acid delivery, focusing on process optimization and enhancing LNP design. Responsibilities: conduct formulation process development, optimize mixing parameters, encapsulation efficiency, and reproducibility; design experiments to improve LNP performance; collaborate on characterization, evaluation, and technology transfer; analyze data and document findings; stay current with advancements in LNP technologies. Requirements: PhD in Chemical Engineering, Pharmaceutical Sciences, Bioengineering, or related field with 3+ years (PhD) or 8+ years (M.S.) of relevant industry experience; strong background in nanoparticle or LNP process development, scale-up, or manufacturing; experience with nucleic acid formulations (e.g., mRNA, DNA), and characterization techniques such as DLS and encapsulation assays; problem-solving and collaboration skills. Preferred: experience in formulation screening, next-generation LNP systems, and early-stage R&D. HighValue: focus on gene delivery, LNP formulation, process scale-up, nucleic acid delivery platforms. WorkSetup: not specified, but collaborative research environment.