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Scientist, In Vivo CAR-T Pipeline

Legend Biotech
September 04, 2026
Full-time
On-site
Philadelphia, PA
Clinical Research and Development
Role: In Vivo CAR-T Pipeline Scientist responsible for advancing cell and gene therapy platforms, focusing on early discovery through preclinical development. Responsibilities include designing and executing in vitro and in vivo studies to evaluate product potency, efficacy, and safety; developing and troubleshooting assays such as cell line engineering, functional cytotoxicity, ELISA, PCR, viral vector production, and high-throughput screening; analyzing complex datasets; and communicating findings effectively to research teams. Requirements: PhD in Immunology, Cell Biology, Molecular Biology, or related field, or Master’s with 3–6+ years’ relevant industry or postdoctoral experience; hands-on expertise in immunology, cell therapy, gene therapy, and viral vector systems (preferably lentivirus). HighValue: cell/gene therapy, immunology, viral vectors, in vivo models, preclinical development, lab-based role in Philadelphia, PA. Collaboration: closely work with research and early development teams. WorkSetup: onsite, lab-based. Travel: not specified.