Scientist II, Upstream Development for Protein Development and Manufacturing

Role: Scientist II in Upstream Process Development within Vaxcyte's Protein Development and CMC team, focusing on bacterial fermentation development for vaccine production. Responsibilities: develop and characterize upstream fermentation processes, operate bioreactors including Ambr 250, optimize process parameters, author SOPs and batch records, analyze data for process improvements, and collaborate across functions such as downstream processing and analytical development. Requirements: PhD (2-5 years), MS (7 years), or BA/BS (10+ years) with relevant biotech/pharma experience; expertise in bacterial fermentation, bioreactor operation, aseptic techniques, and process scale-up is essential; knowledge of primary recovery operations and DoE principles is preferred. High-Value: bacterial vaccine development, fermentation process optimization, lab-scale bioreactor experience, late-stage process characterization. Work Setup: onsite in San Carlos, CA, with a competitive salary range of $146,000–$171,000 and comprehensive benefits.