Scientist I, Radiopharmacology

Role Summary

Scientist I, Radiopharmacology

Responsibilities

• Design and execute radiolabeling reactions using a range of isotopes, including Lu-177, Ac-225, In-111, Zr-89, At-211, I-131, and Pb-212.
• Perform conjugation reactions between bifunctional chelators and peptides or proteins.
• Develop and optimize radiochemical synthesis protocols for both diagnostic and therapeutic applications.
• Conduct quality control and stability testing of radiolabeled
• Analyze experimental data, interpret results, and communicate findings to cross-functional teams.
• Support preclinical research studies, including biodistribution, pharmacokinetics, and dosimetry assessments.
• Prepare, review, and ensure compliance of study protocols and technical reports
• Train and mentor junior staff in radiochemistry techniques, radiation safety, and handling of radioactive materials.
• Maintain accurate laboratory records
• Stay current with advancements in radiochemistry, nuclear medicine, and isotope production technologies.
• Assist in the evaluation and implementation of new equipment, automation systems, and analytical tools.
• Other duties may be assigned verbally at any time.

Qualifications

• PhD in a relevant field (e.g., radiochemistry, chemistry, biochemistry, pharmaceutical sciences).
• Expertise in radiochemistry, radiobiology, molecular imaging, and therapeutic radionuclide production.
• Experience with analysis and interpretation in vivo data of radioconjugates.
• Strong computer, organizational, and multitasking skills.
• Excellent communication skills.

Skills

• Expertise in radiochemistry, radiobiology, molecular imaging, and therapeutic radionuclide production and handling.
• Expertise in chromatography techniques such as thin-layer chromatography (TLC), column chromatography, high-performance liquid chromatography (HPLC).
• Expertise in conducting in vivo studies using radiolabeled compounds
• Experience with analysis and interpretation in vivo data of radioconjugate pharmaceuticals.

Education

• PhD in a relevant field (e.g., radiochemistry, chemistry, biochemistry, pharmaceutical sciences).
• Expertise in radiochemistry, radiobiology, molecular imaging, and therapeutic radionuclide production.
• Experience with analysis and interpretation in vivo data of radioconjugates.
• Strong computer, organizational, and multitasking skills.
• Excellent communication skills.

Additional Requirements

• Must be able to sit and use hands to finger, handle and feel.
• Must be able to lift and move packages weighing up to 50 pounds.
• Must be able to sit for long periods of time using a computer in a typical office environment in a multi-level facility.
• Some activities require repetitive motion and reaching, pulling, or pushing.
• In carrying out the duties of the job there will be frequent exposure to fumes and chemical hazards
• Duties performed routinely require exposure to blood, body fluid and tissue.