Scientist I, Purification

Role Summary

Scientist I, Purification based in Redmond, WA. Reports to the Sr. Scientist II, Purification. You will contribute to purification process development for biotherapeutics, collaborate with cross-functional teams, and transfer processes to clinical and commercial manufacturing. You’ll develop technologies to reduce cost and improve efficiency, and regularly share findings and results.

Responsibilities

• Dive deep into purification process development for biotherapeutics manufacturing, always looking for ways to improve and innovate.
• Collaborate with cross-functional teams to explore new possibilities and solutions.
• Transfer processes to clinical and commercial manufacturing facilities.
• Technology development to reduce the cost and improve the efficiency of purification processes.
• Regularly share your findings, ideas, and solutions in both team settings and presentations.
• Ensure that curiosity-driven questions and exploration lead to measurable, impactful results.

Qualifications

• Required: BS or MS degree in Engineering, Biochemistry, or related field and 5+ years of experience or Ph.D.
• Required: Knowledgeable in chromatography and filtration theory, downstream development strategy, and process scale-up/transfer
• Required: Experience with chromatography operations, including operating AKTA systems
• Required: Experience with filtration operation, including executing bench-scale dead-end filtration, viral filtration, UF/DF, and depth filtration
• Required/Preferred: Excellent communicator, both verbally and in writing, able to share complex ideas in a simple, relatable way.
• Preferred: Experience with design of experiments (DOE) and analysis using statistical software packages (JMP, MATLAB, etc.)
• Preferred: Experience with multi column chromatography
• Preferred: Experience with continuous and connected processing
• Preferred: Experience with process modelling
• Preferred: A curious problem-solver with a passion for learning and growing in a dynamic environment.
• Preferred: Comfortable with ambiguity and thrives in environments where curiosity and experimentation are encouraged.
• Preferred: A self-starter who takes initiative, owns your projects, and actively seeks out new challenges.

Skills

• Knowledge of chromatography and filtration theory; downstream development strategy; and process scale-up/transfer
• Experience with chromatography operations, including AKTA systems
• Experience with filtration operations, including dead-end filtration, viral filtration, UF/DF, and depth filtration
• DOE and analysis using statistical software (JMP, MATLAB, etc.)
• Experience with multi-column chromatography
• Experience with continuous and connected processing
• Experience with process modelling
• Strong verbal and written communication; ability to present complex ideas clearly
• Self-starter with initiative and adaptability

Education

• BS or MS degree in Engineering, Biochemistry, or related field