Scientist I, Preformulation

Role: Preformulation Pharmaceutical Scientist in early drug discovery, focusing on small molecule candidates for cardiovascular indications. Responsibilities: conduct preformulation assessments including solubility, stability, polymorphism, and solid-form screening; develop formulations for non-clinical PK, pharmacology, and toxicology studies; lead laboratory work, oversee CRO activities, and contribute to candidate selection and regulatory documentation. Requirements: MS or PhD in Pharmaceutical Sciences, Chemistry, or related field; 4+ years (PhD) or 7+ years (MS) industry experience with preformulation and preclinical formulation; hands-on expertise with poorly soluble compounds, HPLC/UPLC analysis, solubility assays, and solid-state properties. High-Value: experience with biopharmaceutics, pharmacokinetics, GLP toxicology support, and formulation at CROs; background in cardiovascular drug development; knowledge of solid-form screening, solubility-enabling technologies, and dose verification. WorkSetup: based in South San Francisco, CA with competitive salary; additional benefits included.