Scientist I, Multi-Specifics Expression

Role: Protein expression scientist specializing in mammalian (CHO) cell line engineering for biologics, supporting AbbVie's biologics discovery and development efforts. Responsibilities: generate and screen stable CHO cell lines expressing complex multi-specific biologics, optimize process development (batch and fed-batch bioreactors), characterize cell lines via molecular tools (ddPCR, FACS), implement automation and high-throughput workflows, troubleshoot expression challenges, and perform analytical characterization of samples. Qualifications: Bachelor's or Master’s in biology, chemistry, or biochemistry; 5+ (BS) or 2+ (MS) years hands-on experience in mammalian cell culture, biologic expression, and cell line development; familiarity with multi-specific molecule stability, process optimization, automation, and molecular tools like FACS and ddPCR. Preferred: experience with targeted integration, Wave bioreactors, glycosylation, aggregation, and vector design. High-value specifics include focus on complex biologics (multi-specifics), process development, molecular characterization, and automation technologies, supporting immunology, oncology, and neuroscience indications. Collaboration with research and development teams, with work supported in a laboratory setting; location details and travel expectations are not specified.