Scientist I, In Vitro Technologies - Discovery Biotherapeutics
AbbVie
August 30, 2026
Remote friendly (Worcester, MA)
United States
$75,000 - $142,500 USD yearly
Clinical Research and Development
Job Description
Discovery Biotherapeutics and Genetic Medicine seeks a highly motivated research scientist to support biologics drug discovery and engineering. Responsibilities include designing and executing in vitro display technologies for lead antibody identification and optimization; collaborating to generate stage-gate appropriate in vitro, cellular, and in vivo data packages supporting proof-of-concept (PoC); and developing/implementing research for discovery, optimization, and mechanistic understanding of molecular pharmacology of therapeutic molecules. Analyze, document, and report data effectively and present in group settings.
Qualifications
Education: BS or MS in Biology or a related field with typically 5+ years of experience (BS) or 2+ years (MS) in a pharmaceutical and/or relevant research environment.
Required Skills & Experience
- Strong molecular biology skills (e.g., molecular cloning)
- Familiarity with sequence analysis tools (e.g., Geneious, Genedata, PipeBio)
- Experience with biologics, antibodies, antibody fragments, and mimetics
- Experience with bacterial cell culture
- Solid understanding of protein structure and function
- Excellent oral and written communication skills
- Ability to engage scientific leaders in collaborative research
- Strong organizational skills; manage multiple projects
- Team player in fast-paced, multi-disciplinary environment
- Ability to adapt to changing priorities and timelines
- Proficiency with MS Office Suite (Excel, PowerPoint, Word)
Preferred Skills & Experience
- In vitro antibody discovery display technologies (e.g., phage display, yeast display)
- Binding assays (e.g., ELISA, flow cytometry)
- Antibody engineering/optimization (e.g., affinity modulation, liability engineering, humanization)
- Antibody library design and construction
- Mammalian cell culture
- Automation of biologics discovery processes
- Proficiency with Prism, Geneious, Sequencher, and/or Genedata
- Familiarity with computational approaches and working with AI/ML and Digital Transformation teams
Benefits
- Paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees
- Eligible for short-term incentive programs
Discovery Biotherapeutics and Genetic Medicine seeks a highly motivated research scientist to support biologics drug discovery and engineering. Responsibilities include designing and executing in vitro display technologies for lead antibody identification and optimization; collaborating to generate stage-gate appropriate in vitro, cellular, and in vivo data packages supporting proof-of-concept (PoC); and developing/implementing research for discovery, optimization, and mechanistic understanding of molecular pharmacology of therapeutic molecules. Analyze, document, and report data effectively and present in group settings.
Qualifications
Education: BS or MS in Biology or a related field with typically 5+ years of experience (BS) or 2+ years (MS) in a pharmaceutical and/or relevant research environment.
Required Skills & Experience
- Strong molecular biology skills (e.g., molecular cloning)
- Familiarity with sequence analysis tools (e.g., Geneious, Genedata, PipeBio)
- Experience with biologics, antibodies, antibody fragments, and mimetics
- Experience with bacterial cell culture
- Solid understanding of protein structure and function
- Excellent oral and written communication skills
- Ability to engage scientific leaders in collaborative research
- Strong organizational skills; manage multiple projects
- Team player in fast-paced, multi-disciplinary environment
- Ability to adapt to changing priorities and timelines
- Proficiency with MS Office Suite (Excel, PowerPoint, Word)
Preferred Skills & Experience
- In vitro antibody discovery display technologies (e.g., phage display, yeast display)
- Binding assays (e.g., ELISA, flow cytometry)
- Antibody engineering/optimization (e.g., affinity modulation, liability engineering, humanization)
- Antibody library design and construction
- Mammalian cell culture
- Automation of biologics discovery processes
- Proficiency with Prism, Geneious, Sequencher, and/or Genedata
- Familiarity with computational approaches and working with AI/ML and Digital Transformation teams
Benefits
- Paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees
- Eligible for short-term incentive programs