Scientist I

Role Summary

Responsibilities

• Develop and optimize physiologically relevant in vitro models, including providing technical expertise, design and execute qualification plans, and establish relevant endpoint assays to dissect the molecular mechanisms of toxicity.
• Independently review literature to generate hypotheses for experimental testing. Design and execute relevant experiments to test hypotheses, including data analysis and its interpretation.
• Collaborate with external vendors on technology and assay evaluation, where appropriate.
• Work with project teams to address and investigate safety mechanisms and help projects meet development timelines.
• Author investigative reports to support inclusion of results in regulatory submissions as needed.
• Represent Sanofi on external consortia.

Qualifications

• PhD in a biological field with 0-3 years of postdoctoral experience OR Master‚Äôs Degree with 4+ years relevant experience in an academic or biopharmaceutical setting.
• A degree in toxicology, pharmacology, immunology, biomedical engineering, or equivalent is preferred.
• Proven experience and expertise in mammalian cell culture (primary, iPSC), imaging (high content, confocal), molecular biology (RNA, DNA, protein) endpoints, and biochemical endpoints is a must.
• Working knowledge of organ-on-a-chip/MPS, 3D models, or complex in vitro systems will be an advantage.
• Experience in toxicity assays related to liver, kidney or immunology is also a plus.
• Established record of scientific contribution in peer-reviewed journals and scientific symposiums.
• Excellent verbal and written communication skills.

Skills

• In vitro model development and validation
• Literature review and hypothesis generation
• Collaborative work with internal and external partners

Education

• PhD in biological field or Master‚Äôs with relevant experience as specified above.

Additional Requirements

• Occasional domestic travel to scientific conferences as permitted by travel policies. Availability to start in Q1 2026.
• The position is lab-based and requires on-site work in Cambridge, MA.