Scientist I, Biologics Outsourcing Specialist
AbbVie
August 13, 2026
Remote friendly (North Chicago, IL)
United States
$75,000 - $142,500 USD yearly
Operations
Overview:
- Coordinate and manage biologics generation outsourcing at CROs (protein production for hundreds of biologics molecules/year; 100 mg to 50 grams).
Key Responsibilities:
- Execute and coordinate CRO outsourcing for therapeutic biologic production and purification requests.
- Collaborate with CRO vendors and manage protein production activities (ordering, sequence design, expression method, scale selection, primary capture, secondary purification, QC/analytical work).
- Plan and manage outsourcing projects to ensure timely, successful execution, including risk management.
- Manage pre- and post-registration of generated molecules in IT systems.
- Develop two-way vendor data sharing to enable tracking and LIMS data import.
- Perform biophysical/analytical QC beyond vendor offerings (SEC, intact/reduced mass spectrometry, endotoxin, HCP).
- Align vendor QC methodologies to internal standards; drive equivalent QC packages to reduce need for internal QC.
- Communicate project status, results, and unexpected observations; resolve scientific issues with novel approaches.
- Independently design, execute, and interpret experiments; analyze, document, and report data.
Qualifications:
- BS or MS in biology, chemistry, biochemistry, or related field (typically 5+ years with BS or 2+ years with MS).
- Biologics production experience: expression plasmid design; stable/transient CHO expression; Protein A/CHO1/kappa select; AEX/CEX/HIC purification.
- CRO experience in protein production.
- Analytical QC experience: SEC, intact/reduced MS, endotoxin, HCP, peptide mapping, released glycan analysis, CE-SDS.
- Process development/optimization experience.
- Ability to overcome challenges (low expression, aggregation, glycosylation issues, chain pairing, separations).
Benefits (if applicable):
- Paid time off; medical/dental/vision insurance; 401(k); eligible for short-term incentive programs.
- Coordinate and manage biologics generation outsourcing at CROs (protein production for hundreds of biologics molecules/year; 100 mg to 50 grams).
Key Responsibilities:
- Execute and coordinate CRO outsourcing for therapeutic biologic production and purification requests.
- Collaborate with CRO vendors and manage protein production activities (ordering, sequence design, expression method, scale selection, primary capture, secondary purification, QC/analytical work).
- Plan and manage outsourcing projects to ensure timely, successful execution, including risk management.
- Manage pre- and post-registration of generated molecules in IT systems.
- Develop two-way vendor data sharing to enable tracking and LIMS data import.
- Perform biophysical/analytical QC beyond vendor offerings (SEC, intact/reduced mass spectrometry, endotoxin, HCP).
- Align vendor QC methodologies to internal standards; drive equivalent QC packages to reduce need for internal QC.
- Communicate project status, results, and unexpected observations; resolve scientific issues with novel approaches.
- Independently design, execute, and interpret experiments; analyze, document, and report data.
Qualifications:
- BS or MS in biology, chemistry, biochemistry, or related field (typically 5+ years with BS or 2+ years with MS).
- Biologics production experience: expression plasmid design; stable/transient CHO expression; Protein A/CHO1/kappa select; AEX/CEX/HIC purification.
- CRO experience in protein production.
- Analytical QC experience: SEC, intact/reduced MS, endotoxin, HCP, peptide mapping, released glycan analysis, CE-SDS.
- Process development/optimization experience.
- Ability to overcome challenges (low expression, aggregation, glycosylation issues, chain pairing, separations).
Benefits (if applicable):
- Paid time off; medical/dental/vision insurance; 401(k); eligible for short-term incentive programs.