Scientist I
Codexis, Inc.
5 days ago
On-site
Redwood City, CA
Clinical Research and Development
Responsibilities:
- Develop synthesis and downstream process parameters for therapeutically relevant compounds using enzymatic approaches.
- Screen starting raw materials for process inputs and identify commercially viable supplies.
- Develop bench and pilot-scale unit operations including nanofiltration, purification, ultrafiltration, and depth filtration.
- Provide troubleshooting support to commercial and project management.
- Lead multidisciplinary teams, direct projects, and communicate results/challenges to key stakeholders.
- Supervise technical support staff.
- Identify and evaluate new technologies for ECO synthesis processes.
Required qualifications/skills:
- Ph.D. in Chemistry, Chemical Engineering, Biochemistry, or related discipline with 0–3 years relevant industrial experience; or B.S. with at least 10 years relevant industrial experience.
- Strong knowledge of chemistry/chemical engineering and enzyme physiology with practical process engineering flow applications.
- Experimental design and data analysis including Design of Experiments (DOE).
- Unicorn software; cGMP regulation understanding and flow-based reactor system use (ideal).
Valuable experience:
- Development and transfer of enzyme-catalyzed processes to manufacturing scale.
- Process development and/or scale-up in pharma GMP facilities.
- Flow chemistry process development and/or scale-up for production of pharmaceuticals or fine chemicals.
Job benefits:
- Medical, dental, and vision insurance; basic life, AD&D, short- and long-term disability.
- 401(k) with company match up to 4%; company equity.
- Paid time off including 18 company holidays (with summer and winter shutdown), vacation, and wellness time.
- Annual lifestyle account; ESPP; flexible spending accounts; student debt program; mental health wellness program.
- Subsidized onsite lunch; onsite gym facilities; paid parental leave.
- Develop synthesis and downstream process parameters for therapeutically relevant compounds using enzymatic approaches.
- Screen starting raw materials for process inputs and identify commercially viable supplies.
- Develop bench and pilot-scale unit operations including nanofiltration, purification, ultrafiltration, and depth filtration.
- Provide troubleshooting support to commercial and project management.
- Lead multidisciplinary teams, direct projects, and communicate results/challenges to key stakeholders.
- Supervise technical support staff.
- Identify and evaluate new technologies for ECO synthesis processes.
Required qualifications/skills:
- Ph.D. in Chemistry, Chemical Engineering, Biochemistry, or related discipline with 0–3 years relevant industrial experience; or B.S. with at least 10 years relevant industrial experience.
- Strong knowledge of chemistry/chemical engineering and enzyme physiology with practical process engineering flow applications.
- Experimental design and data analysis including Design of Experiments (DOE).
- Unicorn software; cGMP regulation understanding and flow-based reactor system use (ideal).
Valuable experience:
- Development and transfer of enzyme-catalyzed processes to manufacturing scale.
- Process development and/or scale-up in pharma GMP facilities.
- Flow chemistry process development and/or scale-up for production of pharmaceuticals or fine chemicals.
Job benefits:
- Medical, dental, and vision insurance; basic life, AD&D, short- and long-term disability.
- 401(k) with company match up to 4%; company equity.
- Paid time off including 18 company holidays (with summer and winter shutdown), vacation, and wellness time.
- Annual lifestyle account; ESPP; flexible spending accounts; student debt program; mental health wellness program.
- Subsidized onsite lunch; onsite gym facilities; paid parental leave.