Scientist - Histology and In vivo

Role Summary

We are seeking a dynamic and collaborative scientist to join our cross-functional team, contributing to cutting-edge research at the intersection of in vivo, histology, and in vitro studies. This role requires expertise in designing and executing preclinical studies, developing innovative histological techniques, and supporting in vitro assay development. As a key member of our team, you will work closely with colleagues across multiple disciplines to drive scientific discovery, optimize workflows, and deliver impactful insights that advance our research programs. If you thrive in a fast-paced, interdisciplinary environment and excel at bridging functions, we’d love to hear from you!

Responsibilities

• In Vivo Research
  • Collaborate with cross-functional teams to design, manage, and execute studies utilizing mouse models.
  • Administer compounds through various methods, including intraperitoneal, subcutaneous, and intravenous dosing.
  • Collect, process, and document biological samples (e.g., blood, tissues, organs) for downstream histological and molecular analyses, ensuring alignment with project goals across teams.
• Histology Research & Development (Kidney-specific histological techniques are a plus)
  • Optimization & Validation: Partner with internal teams to develop, refine, and validate histological endpoints to support preclinical research projects.
  • Experimental Execution: Perform a wide range of histological techniques, such as IHC, ICC, RNAscope, and related methods, ensuring rigor and reproducibility while addressing the needs of multiple stakeholders.
  • Sample Management: Coordinate with other teams to handle, fix, embed, section, and prepare biological tissues for high-quality histological analysis.
  • Data Analysis: Collaborate with data scientists and other researchers to utilize imaging and quantitative analysis software, interpret histological data, generate insights, and address research questions.
  • Reporting & Communication: Prepare detailed, clear reports and present findings effectively to internal teams, bridging communication between research and development functions.
  • Innovation: Drive improvements in histological workflows and protocols in collaboration with cross-functional teams to align with program objectives and industry best practices.
• In Vitro Assay Support (Preferred)
  • Work closely with other functional groups to culture mammalian cells and assist in the development of cell-based assays.
  • Apply techniques such as immunocytochemistry and immunoblotting to support mechanistic studies and integrate findings into broader research initiatives.

Qualifications

• Required: B.S. and 6+ years of experience in histology and in vivo techniques.

Skills

• In vivo study design and execution using mouse models
• Histology techniques including IHC, ICC, RNAscope
• Sample processing, fixation, embedding, and tissue sectioning
• Data analysis using imaging and quantitative software; interpretation of histological data
• Cross-functional collaboration and communication of findings
• Cell culture and in vitro assay development; immunocytochemistry and immunoblotting
• Ability to develop and refine histological endpoints and workflows

Education

• Bachelor’s degree in biology, life sciences, or a related field