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Scientist, High-Throughput Protein Expression and Purification

Bristol Myers Squibb
September 10, 2026
Full-time
Remote friendly (Brisbane, CA)
Worldwide
Other
Role: Scientist focused on expanding high-throughput biologics production capabilities within Discovery Biotherapeutics. Primary objectives include executing scalable protein expression, purification, normalization, and characterization workflows to support antibody, multispecific, and other biologics discovery programs. Responsibilities encompass designing and optimizing transient mammalian expression workflows (HEK293, CHO), automating purification processes, maintaining and troubleshooting laboratory automation systems, and developing reproducible, scalable protocols. The role requires close collaboration with Protein Sciences, Molecular Biology, Data Science, and project teams to align production with program timelines and priorities. Qualifications: Bachelor's in biochemistry, bioengineering, or related field with 5+ years, or master's with 3+ years, or Ph.D. with relevant experience; hands-on experience with mammalian protein expression, purification, and quality assessment; proficiency in molecular biology techniques and workflow troubleshooting; strong data analysis, documentation, and collaboration skills. Preferred qualifications include experience with high-throughput workflows, laboratory automation, analytical methods (SEC, HPLC, SDS-PAGE), cell-free expression, scripting (Python/R), and digital data management systems. High-value specifics: biologics discovery support, mammalian expression systems, emphasis on automation, reproducibility, and continuous process improvement; role involves cross-functional teamwork within a fast-paced lab environment. Work setup is not specified, but the focus is on laboratory execution and collaboration.