Scientist, High-Throughput Protein Expression and Purification
Bristol Myers Squibb
September 10, 2026
Full-time
Remote friendly (Brisbane, CA)
Worldwide
Operations
Role: Scientist specializing in high-throughput biologics production within Discovery Biotherapeutics, supporting antibody and multispecific discovery workflows. Responsibilities: execute and optimize scalable mammalian protein expression, purification, normalization, and quality assessment; operate and troubleshoot automation platforms; develop reproducible workflows; collaborate across Protein Sciences, Molecular Biology, Automation, Data Science, and Discovery Biology teams; evaluate emerging technologies for throughput and quality improvements; document and ensure data integrity and safety. Requirements: Bachelor's degree in biochemistry, bioengineering, or related field with 5+ years, or master's with 3+ years, or Ph.D. with relevant experience; hands-on expertise in mammalian expression systems (HEK293/CHO), protein purification, cloning, and high-throughput workflows; strong problem-solving and communication skills; ability to independently design experiments and manage evolving priorities. Preferred: experience with laboratory automation, analytical protein quality methods (SEC, HPLC, SDS-PAGE), cell-free expression, workflow scripting (Python, R), and digital data systems (ELN, LIMS). High-Value: biologics discovery, therapeutic antibodies, multispecifics; workflow automation and scale-up; collaboration with cross-functional teams; focus on throughput, reproducibility, and continuous improvement. Work setup: not explicitly specified; role involves laboratory execution, automation, and cross-team interactions.