Scientist – Erythroid Biology
Amgen
August 12, 2026
Remote friendly (Thousand Oaks, CA)
United States
Other
Scientist – Erythroid Biology
Responsibilities:
- Design and execute in vitro and ex vivo assays to evaluate siRNA delivery and function
- Develop human primary cell-based systems
- Support target validation and mechanism-of-action studies for siRNA therapeutics
- Collaborate with Delivery/chemistry teams, Translational and biomarker teams
- Establish and optimize flow cytometry panels and qPCR/RNA-based readouts
- Contribute to IND-enabling studies and data packages
Basic Qualifications:
- Doctorate degree
- OR Master’s degree and 2 years scientific experience
- OR Bachelor’s degree and 4 years scientific experience
Preferred Qualifications:
- Experience with siRNA/RNA therapeutics (delivery or functional assays), erythroid biology, and hematopoiesis
- Strong background in flow cytometry (multi-color) and cell-based functional assays
- Familiarity with gene expression (qPCR, RNA assays) and target engagement assays; experience working in cross-functional drug discovery teams
- Knowledge of hemoglobinopathies, conjugated delivery systems, CRISPR or gene editing (plus)
Benefits:
- Total Rewards Plan (eligibility-based): health/welfare plans, retirement/savings, financial plans, work/life balance, career development, retirement and savings plan with company contributions, group medical/dental/vision, life/disability insurance, flexible spending accounts, discretionary annual bonus (or field sales incentive), stock-based long-term incentives, time-off plans, and flexible work models where possible.
Application instructions:
- Apply now. Careers site: careers.amgen.com. No application deadline for external/internal postings; applications continue until a sufficient number is received or a candidate is selected.
Responsibilities:
- Design and execute in vitro and ex vivo assays to evaluate siRNA delivery and function
- Develop human primary cell-based systems
- Support target validation and mechanism-of-action studies for siRNA therapeutics
- Collaborate with Delivery/chemistry teams, Translational and biomarker teams
- Establish and optimize flow cytometry panels and qPCR/RNA-based readouts
- Contribute to IND-enabling studies and data packages
Basic Qualifications:
- Doctorate degree
- OR Master’s degree and 2 years scientific experience
- OR Bachelor’s degree and 4 years scientific experience
Preferred Qualifications:
- Experience with siRNA/RNA therapeutics (delivery or functional assays), erythroid biology, and hematopoiesis
- Strong background in flow cytometry (multi-color) and cell-based functional assays
- Familiarity with gene expression (qPCR, RNA assays) and target engagement assays; experience working in cross-functional drug discovery teams
- Knowledge of hemoglobinopathies, conjugated delivery systems, CRISPR or gene editing (plus)
Benefits:
- Total Rewards Plan (eligibility-based): health/welfare plans, retirement/savings, financial plans, work/life balance, career development, retirement and savings plan with company contributions, group medical/dental/vision, life/disability insurance, flexible spending accounts, discretionary annual bonus (or field sales incentive), stock-based long-term incentives, time-off plans, and flexible work models where possible.
Application instructions:
- Apply now. Careers site: careers.amgen.com. No application deadline for external/internal postings; applications continue until a sufficient number is received or a candidate is selected.